{"data":{"id":4839,"citation":"Cheng H., Orr S., Bailey S., Brooun A., Chen P., Deal J., Deng Y., Edwards M., Gallego G., Grodsky N., Huang B., Jalaie M., Kaiser S., Kania R., Kephart S., Lafontaine J., Ornelas M., Pairish M., Planken S., Shen H., Sutton S., Zehnder L., Almaden C., Bagrodia S., Falk M., Gukasyan H., Ho C., Kang X., Kosa R., Liu L., Spilker M., Timofeevski S., Visswanathan R., Wang Z., Meng F., Ren S., Shao L., Xu F., Kath J.: Structure-Based Drug Design and Synthesis of PI3K\u03b1-Selective Inhibitor (PF-06843195). Journal of Medicinal Chemistry, Volume 64 (1), 2020","title":"Structure-Based Drug Design and Synthesis of PI3K\u03b1-Selective Inhibitor (PF-06843195)","doi":"10.1021\/acs.jmedchem.0c01652","doi_url":"https:\/\/doi.org\/10.1021\/acs.jmedchem.0c01652","pmid":null,"year":2020,"journal":"Journal of Medicinal Chemistry","volume":"64","issue":"1","page":null,"authors":[{"first_name":"Hengmiao","last_name":"Cheng","full_name":"Hengmiao Cheng"},{"first_name":"Suvi T. M.","last_name":"Orr","full_name":"Suvi T. M. Orr"},{"first_name":"Simon","last_name":"Bailey","full_name":"Simon Bailey"},{"first_name":"Alexei","last_name":"Brooun","full_name":"Alexei Brooun"},{"first_name":"Ping","last_name":"Chen","full_name":"Ping Chen"},{"first_name":"Judith G.","last_name":"Deal","full_name":"Judith G. Deal"},{"first_name":"Yali L.","last_name":"Deng","full_name":"Yali L. Deng"},{"first_name":"Martin P.","last_name":"Edwards","full_name":"Martin P. Edwards"},{"first_name":"Gary M.","last_name":"Gallego","full_name":"Gary M. Gallego"},{"first_name":"Neil","last_name":"Grodsky","full_name":"Neil Grodsky"},{"first_name":"Buwen","last_name":"Huang","full_name":"Buwen Huang"},{"first_name":"Mehran","last_name":"Jalaie","full_name":"Mehran Jalaie"},{"first_name":"Stephen","last_name":"Kaiser","full_name":"Stephen Kaiser"},{"first_name":"Robert S.","last_name":"Kania","full_name":"Robert S. Kania"},{"first_name":"Susan E.","last_name":"Kephart","full_name":"Susan E. Kephart"},{"first_name":"Jennifer","last_name":"Lafontaine","full_name":"Jennifer Lafontaine"},{"first_name":"Martha A.","last_name":"Ornelas","full_name":"Martha A. Ornelas"},{"first_name":"Mason","last_name":"Pairish","full_name":"Mason Pairish"},{"first_name":"Simon","last_name":"Planken","full_name":"Simon Planken"},{"first_name":"Hong","last_name":"Shen","full_name":"Hong Shen"},{"first_name":"Scott","last_name":"Sutton","full_name":"Scott Sutton"},{"first_name":"Luke","last_name":"Zehnder","full_name":"Luke Zehnder"},{"first_name":"Chau D.","last_name":"Almaden","full_name":"Chau D. Almaden"},{"first_name":"Shubha","last_name":"Bagrodia","full_name":"Shubha Bagrodia"},{"first_name":"Matthew D.","last_name":"Falk","full_name":"Matthew D. Falk"},{"first_name":"Hovhannes J.","last_name":"Gukasyan","full_name":"Hovhannes J. Gukasyan"},{"first_name":"Caroline","last_name":"Ho","full_name":"Caroline Ho"},{"first_name":"Xiaolin","last_name":"Kang","full_name":"Xiaolin Kang"},{"first_name":"Rachel E.","last_name":"Kosa","full_name":"Rachel E. Kosa"},{"first_name":"Ling","last_name":"Liu","full_name":"Ling Liu"},{"first_name":"Mary E.","last_name":"Spilker","full_name":"Mary E. Spilker"},{"first_name":"Sergei","last_name":"Timofeevski","full_name":"Sergei Timofeevski"},{"first_name":"Ravi","last_name":"Visswanathan","full_name":"Ravi Visswanathan"},{"first_name":"Zhenxiong","last_name":"Wang","full_name":"Zhenxiong Wang"},{"first_name":"Fanxiu","last_name":"Meng","full_name":"Fanxiu Meng"},{"first_name":"Shijian","last_name":"Ren","full_name":"Shijian Ren"},{"first_name":"Li","last_name":"Shao","full_name":"Li Shao"},{"first_name":"Feng","last_name":"Xu","full_name":"Feng Xu"},{"first_name":"John C.","last_name":"Kath","full_name":"John C. Kath"}],"url":"https:\/\/molmedb.upol.cz\/api\/v1\/publications\/4839","landing_page":"https:\/\/molmedb.upol.cz\/publication\/4839","created_at":"2026-06-22T14:36:15.000000Z","updated_at":"2026-06-22T14:36:15.000000Z"}}