{"data":{"id":4834,"citation":"Schnute M., Wennerst\u00e5l M., Alley J., Bengtsson M., Blinn J., Bolten C., Braden T., Bonn T., Carlsson B., Caspers N., Chen M., Choi C., Collis L., Crouse K., F\u00e4rneg\u00e5rdh M., Fennell K., Fish S., Flick A., Goos-Nilsson A., Gullberg H., Harris P., Heasley S., Hegen M., Hromockyj A., Hu X., Husman B., Janosik T., Jones P., Kaila N., Kallin E., Kauppi B., Kiefer J., Knafels J., Koehler K., Kruger L., Kurumbail R., Kyne R., Li W., L\u00f6fstedt J., Long S., Menard C., Mente S., Messing D., Meyers M., Napierata L., N\u00f6teberg D., Nuhant P., Pelc M., Prinsen M., Rh\u00f6nnstad P., Backstr\u00f6m-Rydin E., Sandberg J., Sandstr\u00f6m M., Shah F., Sj\u00f6berg M., Sundell A., Taylor A., Thorarensen A., Trujillo J., Trzupek J., Unwalla R., Vajdos F., Weinberg R., Wood D., Xing L., Zamaratski E., Zapf C., Zhao Y., Wilhelmsson A., Berstein G.: Discovery of 3-Cyano-\n                    <i>N<\/i>\n                    -(3-(1-isobutyrylpiperidin-4-yl)-1-methyl-4-(trifluoromethyl)-1\n                    <i>H<\/i>\n                    -pyrrolo[2,3-...","title":"Discovery of 3-Cyano-\n                    <i>N<\/i>\n                    -(3-(1-isobutyrylpiperidin-4-yl)-1-methyl-4-(trifluoromethyl)-1\n                    <i>H<\/i>\n                    -pyrrolo[2,3-\n                    <i>b<\/i>\n                    ]pyridin-5-yl)benzamide: A Potent, Selective, and Orally Bioavailable Retinoic Acid Receptor-Related Orphan Receptor C2 Inverse Agonist","doi":"10.1021\/acs.jmedchem.8b00392","doi_url":"https:\/\/doi.org\/10.1021\/acs.jmedchem.8b00392","pmid":null,"year":2018,"journal":"Journal of Medicinal Chemistry","volume":"61","issue":"23","page":null,"authors":[{"first_name":"Mark E.","last_name":"Schnute","full_name":"Mark E. Schnute"},{"first_name":"Mattias","last_name":"Wennerst\u00e5l","full_name":"Mattias Wennerst\u00e5l"},{"first_name":"Jennifer","last_name":"Alley","full_name":"Jennifer Alley"},{"first_name":"Martin","last_name":"Bengtsson","full_name":"Martin Bengtsson"},{"first_name":"James R.","last_name":"Blinn","full_name":"James R. Blinn"},{"first_name":"Charles W.","last_name":"Bolten","full_name":"Charles W. Bolten"},{"first_name":"Timothy","last_name":"Braden","full_name":"Timothy Braden"},{"first_name":"Tomas","last_name":"Bonn","full_name":"Tomas Bonn"},{"first_name":"Bo","last_name":"Carlsson","full_name":"Bo Carlsson"},{"first_name":"Nicole","last_name":"Caspers","full_name":"Nicole Caspers"},{"first_name":"Ming","last_name":"Chen","full_name":"Ming Chen"},{"first_name":"Chulho","last_name":"Choi","full_name":"Chulho Choi"},{"first_name":"Leon P.","last_name":"Collis","full_name":"Leon P. Collis"},{"first_name":"Kimberly","last_name":"Crouse","full_name":"Kimberly Crouse"},{"first_name":"Mathias","last_name":"F\u00e4rneg\u00e5rdh","full_name":"Mathias F\u00e4rneg\u00e5rdh"},{"first_name":"Kimberly F.","last_name":"Fennell","full_name":"Kimberly F. Fennell"},{"first_name":"Susan","last_name":"Fish","full_name":"Susan Fish"},{"first_name":"Andrew C.","last_name":"Flick","full_name":"Andrew C. Flick"},{"first_name":"Annika","last_name":"Goos-Nilsson","full_name":"Annika Goos-Nilsson"},{"first_name":"Hjalmar","last_name":"Gullberg","full_name":"Hjalmar Gullberg"},{"first_name":"Peter K.","last_name":"Harris","full_name":"Peter K. Harris"},{"first_name":"Steven E.","last_name":"Heasley","full_name":"Steven E. Heasley"},{"first_name":"Martin","last_name":"Hegen","full_name":"Martin Hegen"},{"first_name":"Alexander E.","last_name":"Hromockyj","full_name":"Alexander E. Hromockyj"},{"first_name":"Xiao","last_name":"Hu","full_name":"Xiao Hu"},{"first_name":"Bolette","last_name":"Husman","full_name":"Bolette Husman"},{"first_name":"Tomasz","last_name":"Janosik","full_name":"Tomasz Janosik"},{"first_name":"Peter","last_name":"Jones","full_name":"Peter Jones"},{"first_name":"Neelu","last_name":"Kaila","full_name":"Neelu Kaila"},{"first_name":"Elisabet","last_name":"Kallin","full_name":"Elisabet Kallin"},{"first_name":"Bj\u00f6rn","last_name":"Kauppi","full_name":"Bj\u00f6rn Kauppi"},{"first_name":"James R.","last_name":"Kiefer","full_name":"James R. Kiefer"},{"first_name":"John","last_name":"Knafels","full_name":"John Knafels"},{"first_name":"Konrad","last_name":"Koehler","full_name":"Konrad Koehler"},{"first_name":"Lars","last_name":"Kruger","full_name":"Lars Kruger"},{"first_name":"Ravi G.","last_name":"Kurumbail","full_name":"Ravi G. Kurumbail"},{"first_name":"Robert E.","last_name":"Kyne","full_name":"Robert E. Kyne"},{"first_name":"Wei","last_name":"Li","full_name":"Wei Li"},{"first_name":"Joakim","last_name":"L\u00f6fstedt","full_name":"Joakim L\u00f6fstedt"},{"first_name":"Scott A.","last_name":"Long","full_name":"Scott A. Long"},{"first_name":"Carol A.","last_name":"Menard","full_name":"Carol A. Menard"},{"first_name":"Scot","last_name":"Mente","full_name":"Scot Mente"},{"first_name":"Dean","last_name":"Messing","full_name":"Dean Messing"},{"first_name":"Marvin J.","last_name":"Meyers","full_name":"Marvin J. Meyers"},{"first_name":"Lee","last_name":"Napierata","full_name":"Lee Napierata"},{"first_name":"Daniel","last_name":"N\u00f6teberg","full_name":"Daniel N\u00f6teberg"},{"first_name":"Philippe","last_name":"Nuhant","full_name":"Philippe Nuhant"},{"first_name":"Matthew J.","last_name":"Pelc","full_name":"Matthew J. Pelc"},{"first_name":"Michael J.","last_name":"Prinsen","full_name":"Michael J. Prinsen"},{"first_name":"Patrik","last_name":"Rh\u00f6nnstad","full_name":"Patrik Rh\u00f6nnstad"},{"first_name":"Eva","last_name":"Backstr\u00f6m-Rydin","full_name":"Eva Backstr\u00f6m-Rydin"},{"first_name":"Johnny","last_name":"Sandberg","full_name":"Johnny Sandberg"},{"first_name":"Maria","last_name":"Sandstr\u00f6m","full_name":"Maria Sandstr\u00f6m"},{"first_name":"Falgun","last_name":"Shah","full_name":"Falgun Shah"},{"first_name":"Maria","last_name":"Sj\u00f6berg","full_name":"Maria Sj\u00f6berg"},{"first_name":"Aron","last_name":"Sundell","full_name":"Aron Sundell"},{"first_name":"Alexandria P.","last_name":"Taylor","full_name":"Alexandria P. Taylor"},{"first_name":"Atli","last_name":"Thorarensen","full_name":"Atli Thorarensen"},{"first_name":"John I.","last_name":"Trujillo","full_name":"John I. Trujillo"},{"first_name":"John D.","last_name":"Trzupek","full_name":"John D. Trzupek"},{"first_name":"Ray","last_name":"Unwalla","full_name":"Ray Unwalla"},{"first_name":"Felix F.","last_name":"Vajdos","full_name":"Felix F. Vajdos"},{"first_name":"Robin A.","last_name":"Weinberg","full_name":"Robin A. Weinberg"},{"first_name":"David C.","last_name":"Wood","full_name":"David C. Wood"},{"first_name":"Li","last_name":"Xing","full_name":"Li Xing"},{"first_name":"Edouard","last_name":"Zamaratski","full_name":"Edouard Zamaratski"},{"first_name":"Christoph W.","last_name":"Zapf","full_name":"Christoph W. Zapf"},{"first_name":"Yajuan","last_name":"Zhao","full_name":"Yajuan Zhao"},{"first_name":"Anna","last_name":"Wilhelmsson","full_name":"Anna Wilhelmsson"},{"first_name":"Gabriel","last_name":"Berstein","full_name":"Gabriel Berstein"}],"url":"https:\/\/molmedb.upol.cz\/api\/v1\/publications\/4834","landing_page":"https:\/\/molmedb.upol.cz\/publication\/4834","created_at":"2026-06-22T14:36:06.000000Z","updated_at":"2026-06-22T14:36:06.000000Z"}}