{"data":{"id":4828,"citation":"Stepan A., Tran T., Helal C., Brown M., Chang C., O\u2019Connor R., De Vivo M., Doran S., Fisher E., Jenkinson S., Karanian D., Kormos B., Sharma R., Walker G., Wright A., Yang E., Brodney M., Wager T., Verhoest P., Obach R.: Late-Stage Microsomal Oxidation Reduces Drug\u2013Drug Interaction and Identifies Phosphodiesterase 2A Inhibitor PF-06815189. ACS Medicinal Chemistry Letters, Volume 9 (2), 2018","title":"Late-Stage Microsomal Oxidation Reduces Drug\u2013Drug Interaction and Identifies Phosphodiesterase 2A Inhibitor PF-06815189","doi":"10.1021\/acsmedchemlett.7b00343","doi_url":"https:\/\/doi.org\/10.1021\/acsmedchemlett.7b00343","pmid":null,"year":2018,"journal":"ACS Medicinal Chemistry Letters","volume":"9","issue":"2","page":null,"authors":[{"first_name":"Antonia F.","last_name":"Stepan","full_name":"Antonia F. Stepan"},{"first_name":"Tuan P.","last_name":"Tran","full_name":"Tuan P. Tran"},{"first_name":"Christopher J.","last_name":"Helal","full_name":"Christopher J. Helal"},{"first_name":"Maria S.","last_name":"Brown","full_name":"Maria S. Brown"},{"first_name":"Cheng","last_name":"Chang","full_name":"Cheng Chang"},{"first_name":"Rebecca E.","last_name":"O\u2019Connor","full_name":"Rebecca E. O\u2019Connor"},{"first_name":"Michael","last_name":"De Vivo","full_name":"Michael De Vivo"},{"first_name":"Shawn D.","last_name":"Doran","full_name":"Shawn D. Doran"},{"first_name":"Ethan L.","last_name":"Fisher","full_name":"Ethan L. Fisher"},{"first_name":"Stephen","last_name":"Jenkinson","full_name":"Stephen Jenkinson"},{"first_name":"David","last_name":"Karanian","full_name":"David Karanian"},{"first_name":"Bethany L.","last_name":"Kormos","full_name":"Bethany L. Kormos"},{"first_name":"Raman","last_name":"Sharma","full_name":"Raman Sharma"},{"first_name":"Gregory S.","last_name":"Walker","full_name":"Gregory S. Walker"},{"first_name":"Ann S.","last_name":"Wright","full_name":"Ann S. Wright"},{"first_name":"Edward X.","last_name":"Yang","full_name":"Edward X. Yang"},{"first_name":"Michael A.","last_name":"Brodney","full_name":"Michael A. Brodney"},{"first_name":"Travis T.","last_name":"Wager","full_name":"Travis T. Wager"},{"first_name":"Patrick R.","last_name":"Verhoest","full_name":"Patrick R. Verhoest"},{"first_name":"R. Scott","last_name":"Obach","full_name":"R. Scott Obach"}],"url":"https:\/\/molmedb.upol.cz\/api\/v1\/publications\/4828","landing_page":"https:\/\/molmedb.upol.cz\/publication\/4828","created_at":"2026-06-22T14:35:54.000000Z","updated_at":"2026-06-22T14:35:54.000000Z"}}