{"data":{"id":4800,"citation":"Vazquez M., Kaila N., Strohbach J., Trzupek J., Brown M., Flanagan M., Mitton-Fry M., Johnson T., TenBrink R., Arnold E., Basak A., Heasley S., Kwon S., Langille J., Parikh M., Griffin S., Casavant J., Duclos B., Fenwick A., Harris T., Han S., Caspers N., Dowty M., Yang X., Banker M., Hegen M., Symanowicz P., Li L., Wang L., Lin T., Jussif J., Clark J., Telliez J., Robinson R., Unwalla R.: Identification of <i>N<\/i>-{<i>cis<\/i>-3-[Methyl(7<i>H<\/i>-pyrrolo[2,3-<i>d<\/i>]pyrimidin-4-yl)amino]cyclobutyl}propane-1-sulfonamide (PF-04965842): A Selective JAK1 Clinical Candidate for the Treatment of Autoimmune Diseases. Journal of Medicinal Chemistry, Volume 61 (3), 2018","title":"Identification of <i>N<\/i>-{<i>cis<\/i>-3-[Methyl(7<i>H<\/i>-pyrrolo[2,3-<i>d<\/i>]pyrimidin-4-yl)amino]cyclobutyl}propane-1-sulfonamide (PF-04965842): A Selective JAK1 Clinical Candidate for the Treatment of Autoimmune Diseases","doi":"10.1021\/acs.jmedchem.7b01598","doi_url":"https:\/\/doi.org\/10.1021\/acs.jmedchem.7b01598","pmid":null,"year":2018,"journal":"Journal of Medicinal Chemistry","volume":"61","issue":"3","page":null,"authors":[{"first_name":"Michael L.","last_name":"Vazquez","full_name":"Michael L. Vazquez"},{"first_name":"Neelu","last_name":"Kaila","full_name":"Neelu Kaila"},{"first_name":"Joseph W.","last_name":"Strohbach","full_name":"Joseph W. Strohbach"},{"first_name":"John D.","last_name":"Trzupek","full_name":"John D. Trzupek"},{"first_name":"Matthew F.","last_name":"Brown","full_name":"Matthew F. Brown"},{"first_name":"Mark E.","last_name":"Flanagan","full_name":"Mark E. Flanagan"},{"first_name":"Mark J.","last_name":"Mitton-Fry","full_name":"Mark J. Mitton-Fry"},{"first_name":"Timothy A.","last_name":"Johnson","full_name":"Timothy A. Johnson"},{"first_name":"Ruth E.","last_name":"TenBrink","full_name":"Ruth E. TenBrink"},{"first_name":"Eric P.","last_name":"Arnold","full_name":"Eric P. Arnold"},{"first_name":"Arindrajit","last_name":"Basak","full_name":"Arindrajit Basak"},{"first_name":"Steven E.","last_name":"Heasley","full_name":"Steven E. Heasley"},{"first_name":"Soojin","last_name":"Kwon","full_name":"Soojin Kwon"},{"first_name":"Jonathan","last_name":"Langille","full_name":"Jonathan Langille"},{"first_name":"Mihir D.","last_name":"Parikh","full_name":"Mihir D. Parikh"},{"first_name":"Sarah H.","last_name":"Griffin","full_name":"Sarah H. Griffin"},{"first_name":"Jeffrey M.","last_name":"Casavant","full_name":"Jeffrey M. Casavant"},{"first_name":"Brian A.","last_name":"Duclos","full_name":"Brian A. Duclos"},{"first_name":"Ashley E.","last_name":"Fenwick","full_name":"Ashley E. Fenwick"},{"first_name":"Thomas M.","last_name":"Harris","full_name":"Thomas M. Harris"},{"first_name":"Seungil","last_name":"Han","full_name":"Seungil Han"},{"first_name":"Nicole","last_name":"Caspers","full_name":"Nicole Caspers"},{"first_name":"Martin E.","last_name":"Dowty","full_name":"Martin E. Dowty"},{"first_name":"Xin","last_name":"Yang","full_name":"Xin Yang"},{"first_name":"Mary Ellen","last_name":"Banker","full_name":"Mary Ellen Banker"},{"first_name":"Martin","last_name":"Hegen","full_name":"Martin Hegen"},{"first_name":"Peter T.","last_name":"Symanowicz","full_name":"Peter T. Symanowicz"},{"first_name":"Li","last_name":"Li","full_name":"Li Li"},{"first_name":"Lu","last_name":"Wang","full_name":"Lu Wang"},{"first_name":"Tsung H.","last_name":"Lin","full_name":"Tsung H. Lin"},{"first_name":"Jason","last_name":"Jussif","full_name":"Jason Jussif"},{"first_name":"James D.","last_name":"Clark","full_name":"James D. Clark"},{"first_name":"Jean-Baptiste","last_name":"Telliez","full_name":"Jean-Baptiste Telliez"},{"first_name":"Ralph P.","last_name":"Robinson","full_name":"Ralph P. Robinson"},{"first_name":"Ray","last_name":"Unwalla","full_name":"Ray Unwalla"}],"url":"https:\/\/molmedb.upol.cz\/api\/v1\/publications\/4800","landing_page":"https:\/\/molmedb.upol.cz\/publication\/4800","created_at":"2026-06-22T14:34:45.000000Z","updated_at":"2026-06-22T14:34:45.000000Z"}}