{"data":{"id":4247,"citation":"Abram M, Jakubiec M, Reeb K, Cheng MH, Gedschold R, Rapacz A, Mogilski S, Soca\u0142a K, Nieoczym D, Szafarz M, Latacz G, Szulczyk B, Kalinowska-T\u0142u\u015bcik J, Gawel K, Esguerra CV, Wyska E, M\u00fcller CE, Bahar I, Fontana ACK, Wla\u017a P, Kami\u0144ski RM, Kami\u0144ski K.: Discovery of (<i>R<\/i>)-<i>N<\/i>-Benzyl-2-(2,5-dioxopyrrolidin-1-yl)propanamide [<b>(<i>R<\/i>)-AS-1<\/b>], a Novel Orally Bioavailable EAAT2 Modulator with Drug-like Properties and Potent Antiseizure Activity <i>In Vivo<\/i>. J Med Chem, Volume 65 (17), 2022","title":"Discovery of (<i>R<\/i>)-<i>N<\/i>-Benzyl-2-(2,5-dioxopyrrolidin-1-yl)propanamide [<b>(<i>R<\/i>)-AS-1<\/b>], a Novel Orally Bioavailable EAAT2 Modulator with Drug-like Properties and Potent Antiseizure Activity <i>In Vivo<\/i>.","doi":"10.1021\/acs.jmedchem.2c00534","doi_url":"https:\/\/doi.org\/10.1021\/acs.jmedchem.2c00534","pmid":"35984707","pmid_url":"https:\/\/pubmed.ncbi.nlm.nih.gov\/35984707\/","year":2022,"journal":"J Med Chem","volume":"65","issue":"17","page":"11703-11725","authors":[{"first_name":"Abram M","last_name":null,"full_name":null},{"first_name":"Bahar I","last_name":null,"full_name":null},{"first_name":"Cheng MH","last_name":null,"full_name":null},{"first_name":"Esguerra CV","last_name":null,"full_name":null},{"first_name":"Fontana ACK","last_name":null,"full_name":null},{"first_name":"Gawel K","last_name":null,"full_name":null},{"first_name":"Gedschold R","last_name":null,"full_name":null},{"first_name":"Jakubiec M","last_name":null,"full_name":null},{"first_name":"Kalinowska-T\u0142u\u015bcik J","last_name":null,"full_name":null},{"first_name":"Kami\u0144ski K.","last_name":null,"full_name":null},{"first_name":"Kami\u0144ski RM","last_name":null,"full_name":null},{"first_name":"Latacz G","last_name":null,"full_name":null},{"first_name":"Mogilski S","last_name":null,"full_name":null},{"first_name":"M\u00fcller CE","last_name":null,"full_name":null},{"first_name":"Nieoczym D","last_name":null,"full_name":null},{"first_name":"Rapacz A","last_name":null,"full_name":null},{"first_name":"Reeb K","last_name":null,"full_name":null},{"first_name":"Soca\u0142a K","last_name":null,"full_name":null},{"first_name":"Szafarz M","last_name":null,"full_name":null},{"first_name":"Szulczyk B","last_name":null,"full_name":null},{"first_name":"Wla\u017a P","last_name":null,"full_name":null},{"first_name":"Wyska E","last_name":null,"full_name":null}],"url":"https:\/\/molmedb.upol.cz\/api\/v1\/publications\/4247","landing_page":"https:\/\/molmedb.upol.cz\/publication\/4247","created_at":"2024-05-24T08:49:35.000000Z","updated_at":null}}