{"data":{"id":4237,"citation":"Poddutoori R, Aardalen K, Aithal K, Barahagar SS, Belliappa C, Bock M, Chelur S, Gerken A, Gopinath S, Gruenenfelder B, Kiffe M, Krishnaswami M, Langowski J, Madapa S, Narayanan K, Pandit C, Panigrahi SK, Perrone M, Potakamuri RK, Ramachandra M, Ramanathan A, Ramos R, Sager E, Samajdar S, Subramanya HS, Thimmasandra DS, Venetsanakos E, M\u00f6bitz H.: Discovery of MAP855, an Efficacious and Selective MEK1\/2 Inhibitor with an ATP-Competitive Mode of Action. J Med Chem, Volume 65 (5), 2022","title":"Discovery of MAP855, an Efficacious and Selective MEK1\/2 Inhibitor with an ATP-Competitive Mode of Action.","doi":"10.1021\/acs.jmedchem.1c02192","doi_url":"https:\/\/doi.org\/10.1021\/acs.jmedchem.1c02192","pmid":"35195996","pmid_url":"https:\/\/pubmed.ncbi.nlm.nih.gov\/35195996\/","year":2022,"journal":"J Med Chem","volume":"65","issue":"5","page":"4350-4366","authors":[{"first_name":"Aardalen K","last_name":null,"full_name":null},{"first_name":"Aithal K","last_name":null,"full_name":null},{"first_name":"Barahagar SS","last_name":null,"full_name":null},{"first_name":"Belliappa C","last_name":null,"full_name":null},{"first_name":"Bock M","last_name":null,"full_name":null},{"first_name":"Chelur S","last_name":null,"full_name":null},{"first_name":"Gerken A","last_name":null,"full_name":null},{"first_name":"Gopinath S","last_name":null,"full_name":null},{"first_name":"Gruenenfelder B","last_name":null,"full_name":null},{"first_name":"Kiffe M","last_name":null,"full_name":null},{"first_name":"Krishnaswami M","last_name":null,"full_name":null},{"first_name":"Langowski J","last_name":null,"full_name":null},{"first_name":"Madapa S","last_name":null,"full_name":null},{"first_name":"M\u00f6bitz H.","last_name":null,"full_name":null},{"first_name":"Narayanan K","last_name":null,"full_name":null},{"first_name":"Pandit C","last_name":null,"full_name":null},{"first_name":"Panigrahi SK","last_name":null,"full_name":null},{"first_name":"Perrone M","last_name":null,"full_name":null},{"first_name":"Poddutoori R","last_name":null,"full_name":null},{"first_name":"Potakamuri RK","last_name":null,"full_name":null},{"first_name":"Ramachandra M","last_name":null,"full_name":null},{"first_name":"Ramanathan A","last_name":null,"full_name":null},{"first_name":"Ramos R","last_name":null,"full_name":null},{"first_name":"Sager E","last_name":null,"full_name":null},{"first_name":"Samajdar S","last_name":null,"full_name":null},{"first_name":"Subramanya HS","last_name":null,"full_name":null},{"first_name":"Thimmasandra DS","last_name":null,"full_name":null},{"first_name":"Venetsanakos E","last_name":null,"full_name":null}],"url":"https:\/\/molmedb.upol.cz\/api\/v1\/publications\/4237","landing_page":"https:\/\/molmedb.upol.cz\/publication\/4237","created_at":"2024-05-24T08:49:31.000000Z","updated_at":null}}