{"data":{"id":4080,"citation":"Barrett SD, Holt MC, Kramer JB, Germain B, Ho CS, Ciske FL, Kornilov A, Colombo JM, Uzieblo A, O'Malley JP, Owen TA, Stein AJ, Morano MI.: Difluoromethylene at the \u03b3-Lactam \u03b1-Position Improves 11-Deoxy-8-aza-PGE<sub>1<\/sub> Series EP<sub>4<\/sub> Receptor Binding and Activity: 11-Deoxy-10,10-difluoro-8-aza-PGE<sub>1<\/sub> Analog (KMN-159) as a Potent EP<sub>4<\/sub> Agonist. J Med Chem, Volume 62 (9), 2019","title":"Difluoromethylene at the \u03b3-Lactam \u03b1-Position Improves 11-Deoxy-8-aza-PGE<sub>1<\/sub> Series EP<sub>4<\/sub> Receptor Binding and Activity: 11-Deoxy-10,10-difluoro-8-aza-PGE<sub>1<\/sub> Analog (KMN-159) as a Potent EP<sub>4<\/sub> Agonist.","doi":"10.1021\/acs.jmedchem.9b00336","doi_url":"https:\/\/doi.org\/10.1021\/acs.jmedchem.9b00336","pmid":"30964292","pmid_url":"https:\/\/pubmed.ncbi.nlm.nih.gov\/30964292\/","year":2019,"journal":"J Med Chem","volume":"62","issue":"9","page":"4731-4741","authors":[{"first_name":"Barrett SD","last_name":null,"full_name":null},{"first_name":"Ciske FL","last_name":null,"full_name":null},{"first_name":"Colombo JM","last_name":null,"full_name":null},{"first_name":"Germain B","last_name":null,"full_name":null},{"first_name":"Ho CS","last_name":null,"full_name":null},{"first_name":"Holt MC","last_name":null,"full_name":null},{"first_name":"Kornilov A","last_name":null,"full_name":null},{"first_name":"Kramer JB","last_name":null,"full_name":null},{"first_name":"Morano MI.","last_name":null,"full_name":null},{"first_name":"O'Malley JP","last_name":null,"full_name":null},{"first_name":"Owen TA","last_name":null,"full_name":null},{"first_name":"Stein AJ","last_name":null,"full_name":null},{"first_name":"Uzieblo A","last_name":null,"full_name":null}],"url":"https:\/\/molmedb.upol.cz\/api\/v1\/publications\/4080","landing_page":"https:\/\/molmedb.upol.cz\/publication\/4080","created_at":"2024-05-21T20:14:58.000000Z","updated_at":null}}