{"data":{"id":4073,"citation":"Gentry PR, Kokubo M, Bridges TM, Noetzel MJ, Cho HP, Lamsal A, Smith E, Chase P, Hodder PS, Niswender CM, Daniels JS, Conn PJ, Lindsley CW, Wood MR.: Development of a highly potent, novel M5 positive allosteric modulator (PAM) demonstrating CNS exposure: 1-((1H-indazol-5-yl)sulfoneyl)-N-ethyl-N-(2-(trifluoromethyl)benzyl)piperidine-4-carboxamide (ML380). J Med Chem, Volume 57 (18), 2014","title":"Development of a highly potent, novel M5 positive allosteric modulator (PAM) demonstrating CNS exposure: 1-((1H-indazol-5-yl)sulfoneyl)-N-ethyl-N-(2-(trifluoromethyl)benzyl)piperidine-4-carboxamide (ML380).","doi":"10.1021\/jm500995y","doi_url":"https:\/\/doi.org\/10.1021\/jm500995y","pmid":"25147929","pmid_url":"https:\/\/pubmed.ncbi.nlm.nih.gov\/25147929\/","year":2014,"journal":"J Med Chem","volume":"57","issue":"18","page":"7804-7810","authors":[{"first_name":"Bridges TM","last_name":null,"full_name":null},{"first_name":"Chase P","last_name":null,"full_name":null},{"first_name":"Cho HP","last_name":null,"full_name":null},{"first_name":"Conn PJ","last_name":null,"full_name":null},{"first_name":"Daniels JS","last_name":null,"full_name":null},{"first_name":"Gentry PR","last_name":null,"full_name":null},{"first_name":"Hodder PS","last_name":null,"full_name":null},{"first_name":"Kokubo M","last_name":null,"full_name":null},{"first_name":"Lamsal A","last_name":null,"full_name":null},{"first_name":"Lindsley CW","last_name":null,"full_name":null},{"first_name":"Niswender CM","last_name":null,"full_name":null},{"first_name":"Noetzel MJ","last_name":null,"full_name":null},{"first_name":"Smith E","last_name":null,"full_name":null},{"first_name":"Wood MR.","last_name":null,"full_name":null}],"url":"https:\/\/molmedb.upol.cz\/api\/v1\/publications\/4073","landing_page":"https:\/\/molmedb.upol.cz\/publication\/4073","created_at":"2024-05-21T20:14:56.000000Z","updated_at":null}}