{"data":{"id":4012,"citation":"Hucke O, Coulombe R, Bonneau P, Bertrand-Laperle M, Brochu C, Gillard J, Joly MA, Landry S, Lepage O, Llin\u00e0s-Brunet M, Pesant M, Poirier M, Poirier M, McKercher G, Marquis M, Kukolj G, Beaulieu PL, Stammers TA.: Molecular dynamics simulations and structure-based rational design lead to allosteric HCV NS5B polymerase thumb pocket 2 inhibitor with picomolar cellular replicon potency. J Med Chem, Volume 57 (5), 2014","title":"Molecular dynamics simulations and structure-based rational design lead to allosteric HCV NS5B polymerase thumb pocket 2 inhibitor with picomolar cellular replicon potency.","doi":"10.1021\/jm4004522","doi_url":"https:\/\/doi.org\/10.1021\/jm4004522","pmid":"23773186","pmid_url":"https:\/\/pubmed.ncbi.nlm.nih.gov\/23773186\/","year":2014,"journal":"J Med Chem","volume":"57","issue":"5","page":"1932-1943","authors":[{"first_name":"Beaulieu PL","last_name":null,"full_name":null},{"first_name":"Bertrand-Laperle M","last_name":null,"full_name":null},{"first_name":"Bonneau P","last_name":null,"full_name":null},{"first_name":"Brochu C","last_name":null,"full_name":null},{"first_name":"Coulombe R","last_name":null,"full_name":null},{"first_name":"Gillard J","last_name":null,"full_name":null},{"first_name":"Hucke O","last_name":null,"full_name":null},{"first_name":"Joly MA","last_name":null,"full_name":null},{"first_name":"Kukolj G","last_name":null,"full_name":null},{"first_name":"Landry S","last_name":null,"full_name":null},{"first_name":"Lepage O","last_name":null,"full_name":null},{"first_name":"Llin\u00e0s-Brunet M","last_name":null,"full_name":null},{"first_name":"Marquis M","last_name":null,"full_name":null},{"first_name":"McKercher G","last_name":null,"full_name":null},{"first_name":"Pesant M","last_name":null,"full_name":null},{"first_name":"Poirier M","last_name":null,"full_name":null},{"first_name":"Stammers TA.","last_name":null,"full_name":null}],"url":"https:\/\/molmedb.upol.cz\/api\/v1\/publications\/4012","landing_page":"https:\/\/molmedb.upol.cz\/publication\/4012","created_at":"2024-05-21T20:14:36.000000Z","updated_at":null}}