{"data":{"id":3895,"citation":"Foote KM, Blades K, Cronin A, Fillery S, Guichard SS, Hassall L, Hickson I, Jacq X, Jewsbury PJ, McGuire TM, Nissink JW, Odedra R, Page K, Perkins P, Suleman A, Tam K, Thommes P, Broadhurst R, Wood C.: Discovery of 4-{4-[(3R)-3-Methylmorpholin-4-yl]-6-[1-(methylsulfonyl)cyclopropyl]pyrimidin-2-yl}-1H-indole (AZ20): a potent and selective inhibitor of ATR protein kinase with monotherapy in vivo antitumor activity. J Med Chem, Volume 56 (5), 2013","title":"Discovery of 4-{4-[(3R)-3-Methylmorpholin-4-yl]-6-[1-(methylsulfonyl)cyclopropyl]pyrimidin-2-yl}-1H-indole (AZ20): a potent and selective inhibitor of ATR protein kinase with monotherapy in vivo antitumor activity.","doi":"10.1021\/jm301859s","doi_url":"https:\/\/doi.org\/10.1021\/jm301859s","pmid":"23394205","pmid_url":"https:\/\/pubmed.ncbi.nlm.nih.gov\/23394205\/","year":2013,"journal":"J Med Chem","volume":"56","issue":"5","page":"2125-2138","authors":[{"first_name":"Blades K","last_name":null,"full_name":null},{"first_name":"Broadhurst R","last_name":null,"full_name":null},{"first_name":"Cronin A","last_name":null,"full_name":null},{"first_name":"Fillery S","last_name":null,"full_name":null},{"first_name":"Foote KM","last_name":null,"full_name":null},{"first_name":"Guichard SS","last_name":null,"full_name":null},{"first_name":"Hassall L","last_name":null,"full_name":null},{"first_name":"Hickson I","last_name":null,"full_name":null},{"first_name":"Jacq X","last_name":null,"full_name":null},{"first_name":"Jewsbury PJ","last_name":null,"full_name":null},{"first_name":"McGuire TM","last_name":null,"full_name":null},{"first_name":"Nissink JW","last_name":null,"full_name":null},{"first_name":"Odedra R","last_name":null,"full_name":null},{"first_name":"Page K","last_name":null,"full_name":null},{"first_name":"Perkins P","last_name":null,"full_name":null},{"first_name":"Suleman A","last_name":null,"full_name":null},{"first_name":"Tam K","last_name":null,"full_name":null},{"first_name":"Thommes P","last_name":null,"full_name":null},{"first_name":"Wood C.","last_name":null,"full_name":null}],"url":"https:\/\/molmedb.upol.cz\/api\/v1\/publications\/3895","landing_page":"https:\/\/molmedb.upol.cz\/publication\/3895","created_at":"2024-05-21T20:14:01.000000Z","updated_at":null}}