{"data":{"id":3815,"citation":"Huang A, Moretto A, Janz K, Lowe M, Bedard PW, Tam S, Di L, Clerin V, Sushkova N, Tchernychev B, Tsao DH, Keith JC, Shaw GD, Schaub RG, Wang Q, Kaila N.: Discovery of 2-[1-(4-chlorophenyl)cyclopropyl]-3-hydroxy-8-(trifluoromethyl)quinoline-4-carboxylic acid (PSI-421), a P-selectin inhibitor with improved pharmacokinetic properties and oral efficacy in models of vascular injury. J Med Chem, Volume 53 (16), 2010","title":"Discovery of 2-[1-(4-chlorophenyl)cyclopropyl]-3-hydroxy-8-(trifluoromethyl)quinoline-4-carboxylic acid (PSI-421), a P-selectin inhibitor with improved pharmacokinetic properties and oral efficacy in models of vascular injury.","doi":"10.1021\/jm9013696","doi_url":"https:\/\/doi.org\/10.1021\/jm9013696","pmid":"20718494","pmid_url":"https:\/\/pubmed.ncbi.nlm.nih.gov\/20718494\/","year":2010,"journal":"J Med Chem","volume":"53","issue":"16","page":"6003-6017","authors":[{"first_name":"Bedard PW","last_name":null,"full_name":null},{"first_name":"Clerin V","last_name":null,"full_name":null},{"first_name":"Di L","last_name":null,"full_name":null},{"first_name":"Huang A","last_name":null,"full_name":null},{"first_name":"Janz K","last_name":null,"full_name":null},{"first_name":"Kaila N.","last_name":null,"full_name":null},{"first_name":"Keith JC","last_name":null,"full_name":null},{"first_name":"Lowe M","last_name":null,"full_name":null},{"first_name":"Moretto A","last_name":null,"full_name":null},{"first_name":"Schaub RG","last_name":null,"full_name":null},{"first_name":"Shaw GD","last_name":null,"full_name":null},{"first_name":"Sushkova N","last_name":null,"full_name":null},{"first_name":"Tam S","last_name":null,"full_name":null},{"first_name":"Tchernychev B","last_name":null,"full_name":null},{"first_name":"Tsao DH","last_name":null,"full_name":null},{"first_name":"Wang Q","last_name":null,"full_name":null}],"url":"https:\/\/molmedb.upol.cz\/api\/v1\/publications\/3815","landing_page":"https:\/\/molmedb.upol.cz\/publication\/3815","created_at":"2024-05-21T20:13:32.000000Z","updated_at":null}}