{"data":{"id":3766,"citation":"Cui JJ, McTigue M, Nambu M, Tran-Dub\u00e9 M, Pairish M, Shen H, Jia L, Cheng H, Hoffman J, Le P, Jalaie M, Goetz GH, Ryan K, Grodsky N, Deng YL, Parker M, Timofeevski S, Murray BW, Yamazaki S, Aguirre S, Li Q, Zou H, Christensen J.: Discovery of a novel class of exquisitely selective mesenchymal-epithelial transition factor (c-MET) protein kinase inhibitors and identification of the clinical candidate 2-(4-(1-(quinolin-6-ylmethyl)-1H-[1,2,3]triazolo[4,5-b]pyrazin-6-yl)-1H-pyrazol-1-yl)ethanol (PF-04217903) for the treatment of cancer. J Med Chem, Volume 55 (18), 2012","title":"Discovery of a novel class of exquisitely selective mesenchymal-epithelial transition factor (c-MET) protein kinase inhibitors and identification of the clinical candidate 2-(4-(1-(quinolin-6-ylmethyl)-1H-[1,2,3]triazolo[4,5-b]pyrazin-6-yl)-1H-pyrazol-1-yl)ethanol (PF-04217903) for the treatment of cancer.","doi":"10.1021\/jm300967g","doi_url":"https:\/\/doi.org\/10.1021\/jm300967g","pmid":"22924734","pmid_url":"https:\/\/pubmed.ncbi.nlm.nih.gov\/22924734\/","year":2012,"journal":"J Med Chem","volume":"55","issue":"18","page":"8091-8109","authors":[{"first_name":"Aguirre S","last_name":null,"full_name":null},{"first_name":"Cheng H","last_name":null,"full_name":null},{"first_name":"Christensen J.","last_name":null,"full_name":null},{"first_name":"Cui JJ","last_name":null,"full_name":null},{"first_name":"Deng YL","last_name":null,"full_name":null},{"first_name":"Goetz GH","last_name":null,"full_name":null},{"first_name":"Grodsky N","last_name":null,"full_name":null},{"first_name":"Hoffman J","last_name":null,"full_name":null},{"first_name":"Jalaie M","last_name":null,"full_name":null},{"first_name":"Jia L","last_name":null,"full_name":null},{"first_name":"Le P","last_name":null,"full_name":null},{"first_name":"Li Q","last_name":null,"full_name":null},{"first_name":"McTigue M","last_name":null,"full_name":null},{"first_name":"Murray BW","last_name":null,"full_name":null},{"first_name":"Nambu M","last_name":null,"full_name":null},{"first_name":"Pairish M","last_name":null,"full_name":null},{"first_name":"Parker M","last_name":null,"full_name":null},{"first_name":"Ryan K","last_name":null,"full_name":null},{"first_name":"Shen H","last_name":null,"full_name":null},{"first_name":"Timofeevski S","last_name":null,"full_name":null},{"first_name":"Tran-Dub\u00e9 M","last_name":null,"full_name":null},{"first_name":"Yamazaki S","last_name":null,"full_name":null},{"first_name":"Zou H","last_name":null,"full_name":null}],"url":"https:\/\/molmedb.upol.cz\/api\/v1\/publications\/3766","landing_page":"https:\/\/molmedb.upol.cz\/publication\/3766","created_at":"2024-05-21T20:13:17.000000Z","updated_at":null}}