{"data":{"id":3577,"citation":"Certal V, Halley F, Virone-Oddos A, Delorme C, Karlsson A, Rak A, Thompson F, Filoche-Romm\u00e9 B, El-Ahmad Y, Carry JC, Abecassis PY, Lejeune P, Vincent L, Bonnevaux H, Nicolas JP, Bertrand T, Marquette JP, Michot N, Benard T, Below P, Vade I, Chatreaux F, Lebourg G, Pilorge F, Angouillant-Boniface O, Louboutin A, Lengauer C, Schio L.: Discovery and optimization of new benzimidazole- and benzoxazole-pyrimidone selective PI3K\u03b2 inhibitors for the treatment of phosphatase and TENsin homologue (PTEN)-deficient cancers. J Med Chem, Volume 55 (10), 2012","title":"Discovery and optimization of new benzimidazole- and benzoxazole-pyrimidone selective PI3K\u03b2 inhibitors for the treatment of phosphatase and TENsin homologue (PTEN)-deficient cancers.","doi":"10.1021\/jm300241b","doi_url":"https:\/\/doi.org\/10.1021\/jm300241b","pmid":"22524426","pmid_url":"https:\/\/pubmed.ncbi.nlm.nih.gov\/22524426\/","year":2012,"journal":"J Med Chem","volume":"55","issue":"10","page":"4788-4805","authors":[{"first_name":"Abecassis PY","last_name":null,"full_name":null},{"first_name":"Angouillant-Boniface O","last_name":null,"full_name":null},{"first_name":"Below P","last_name":null,"full_name":null},{"first_name":"Benard T","last_name":null,"full_name":null},{"first_name":"Bertrand T","last_name":null,"full_name":null},{"first_name":"Bonnevaux H","last_name":null,"full_name":null},{"first_name":"Carry JC","last_name":null,"full_name":null},{"first_name":"Certal V","last_name":null,"full_name":null},{"first_name":"Chatreaux F","last_name":null,"full_name":null},{"first_name":"Delorme C","last_name":null,"full_name":null},{"first_name":"El-Ahmad Y","last_name":null,"full_name":null},{"first_name":"Filoche-Romm\u00e9 B","last_name":null,"full_name":null},{"first_name":"Halley F","last_name":null,"full_name":null},{"first_name":"Karlsson A","last_name":null,"full_name":null},{"first_name":"Lebourg G","last_name":null,"full_name":null},{"first_name":"Lejeune P","last_name":null,"full_name":null},{"first_name":"Lengauer C","last_name":null,"full_name":null},{"first_name":"Louboutin A","last_name":null,"full_name":null},{"first_name":"Marquette JP","last_name":null,"full_name":null},{"first_name":"Michot N","last_name":null,"full_name":null},{"first_name":"Nicolas JP","last_name":null,"full_name":null},{"first_name":"Pilorge F","last_name":null,"full_name":null},{"first_name":"Rak A","last_name":null,"full_name":null},{"first_name":"Schio L.","last_name":null,"full_name":null},{"first_name":"Thompson F","last_name":null,"full_name":null},{"first_name":"Vade I","last_name":null,"full_name":null},{"first_name":"Vincent L","last_name":null,"full_name":null},{"first_name":"Virone-Oddos A","last_name":null,"full_name":null}],"url":"https:\/\/molmedb.upol.cz\/api\/v1\/publications\/3577","landing_page":"https:\/\/molmedb.upol.cz\/publication\/3577","created_at":"2024-05-21T20:12:34.000000Z","updated_at":null}}