{"data":{"id":3576,"citation":"Bavetsias V, Lanigan RM, Ruda GF, Atrash B, McLaughlin MG, Tumber A, Mok NY, Le Bihan YV, Dempster S, Boxall KJ, Jeganathan F, Hatch SB, Savitsky P, Velupillai S, Krojer T, England KS, Sejberg J, Thai C, Donovan A, Pal A, Scozzafava G, Bennett JM, Kawamura A, Johansson C, Szykowska A, Gileadi C, Burgess-Brown NA, von Delft F, Oppermann U, Walters Z, Shipley J, Raynaud FI, Westaway SM, Prinjha RK, Fedorov O, Burke R, Schofield CJ, Westwood IM, Bountra C, M\u00fcller S, van Montfort RL, Brennan PE, Blagg J.: 8-Substituted Pyrido[3,4-d]pyrimidin-4(3H)-one Derivatives As Potent, Cell Permeable, KDM4 (JMJD2) and KDM5 (JARID1) Histone Lysine Demethylase Inhibitors. J Med Chem, Volume 59 (4), 2016","title":"8-Substituted Pyrido[3,4-d]pyrimidin-4(3H)-one Derivatives As Potent, Cell Permeable, KDM4 (JMJD2) and KDM5 (JARID1) Histone Lysine Demethylase Inhibitors.","doi":"10.1021\/acs.jmedchem.5b01635","doi_url":"https:\/\/doi.org\/10.1021\/acs.jmedchem.5b01635","pmid":"26741168","pmid_url":"https:\/\/pubmed.ncbi.nlm.nih.gov\/26741168\/","year":2016,"journal":"J Med Chem","volume":"59","issue":"4","page":"1388-1409","authors":[{"first_name":"Atrash B","last_name":null,"full_name":null},{"first_name":"Bavetsias V","last_name":null,"full_name":null},{"first_name":"Bennett JM","last_name":null,"full_name":null},{"first_name":"Blagg J.","last_name":null,"full_name":null},{"first_name":"Bountra C","last_name":null,"full_name":null},{"first_name":"Boxall KJ","last_name":null,"full_name":null},{"first_name":"Brennan PE","last_name":null,"full_name":null},{"first_name":"Burgess-Brown NA","last_name":null,"full_name":null},{"first_name":"Burke R","last_name":null,"full_name":null},{"first_name":"Dempster S","last_name":null,"full_name":null},{"first_name":"Donovan A","last_name":null,"full_name":null},{"first_name":"England KS","last_name":null,"full_name":null},{"first_name":"Fedorov O","last_name":null,"full_name":null},{"first_name":"Gileadi C","last_name":null,"full_name":null},{"first_name":"Hatch SB","last_name":null,"full_name":null},{"first_name":"Jeganathan F","last_name":null,"full_name":null},{"first_name":"Johansson C","last_name":null,"full_name":null},{"first_name":"Kawamura A","last_name":null,"full_name":null},{"first_name":"Krojer T","last_name":null,"full_name":null},{"first_name":"Lanigan RM","last_name":null,"full_name":null},{"first_name":"Le Bihan YV","last_name":null,"full_name":null},{"first_name":"McLaughlin MG","last_name":null,"full_name":null},{"first_name":"Mok NY","last_name":null,"full_name":null},{"first_name":"M\u00fcller S","last_name":null,"full_name":null},{"first_name":"Oppermann U","last_name":null,"full_name":null},{"first_name":"Pal A","last_name":null,"full_name":null},{"first_name":"Prinjha RK","last_name":null,"full_name":null},{"first_name":"Raynaud FI","last_name":null,"full_name":null},{"first_name":"Ruda GF","last_name":null,"full_name":null},{"first_name":"Savitsky P","last_name":null,"full_name":null},{"first_name":"Schofield CJ","last_name":null,"full_name":null},{"first_name":"Scozzafava G","last_name":null,"full_name":null},{"first_name":"Sejberg J","last_name":null,"full_name":null},{"first_name":"Shipley J","last_name":null,"full_name":null},{"first_name":"Szykowska A","last_name":null,"full_name":null},{"first_name":"Thai C","last_name":null,"full_name":null},{"first_name":"Tumber A","last_name":null,"full_name":null},{"first_name":"van Montfort RL","last_name":null,"full_name":null},{"first_name":"Velupillai S","last_name":null,"full_name":null},{"first_name":"von Delft F","last_name":null,"full_name":null},{"first_name":"Walters Z","last_name":null,"full_name":null},{"first_name":"Westaway SM","last_name":null,"full_name":null},{"first_name":"Westwood IM","last_name":null,"full_name":null}],"url":"https:\/\/molmedb.upol.cz\/api\/v1\/publications\/3576","landing_page":"https:\/\/molmedb.upol.cz\/publication\/3576","created_at":"2024-05-21T20:12:33.000000Z","updated_at":null}}