{"data":{"id":3494,"citation":"Su Q, Banks E, Bebernitz G, Bell K, Borenstein CF, Chen H, Chuaqui CE, Deng N, Ferguson AD, Kawatkar S, Grimster NP, Ruston L, Lyne PD, Read JA, Peng X, Pei X, Fawell S, Tang Z, Throner S, Vasbinder MM, Wang H, Winter-Holt J, Woessner R, Wu A, Yang W, Zinda M, Kettle JG.: Discovery of (2<i>R<\/i>)-<i>N<\/i>-[3-[2-[(3-Methoxy-1-methyl-pyrazol-4-yl)amino]pyrimidin-4-yl]-1<i>H<\/i>-indol-7-yl]-2-(4-methylpiperazin-1-yl)propenamide (AZD4205) as a Potent and Selective Janus Kinase 1 Inhibitor. J Med Chem, Volume 63 (9), 2020","title":"Discovery of (2<i>R<\/i>)-<i>N<\/i>-[3-[2-[(3-Methoxy-1-methyl-pyrazol-4-yl)amino]pyrimidin-4-yl]-1<i>H<\/i>-indol-7-yl]-2-(4-methylpiperazin-1-yl)propenamide (AZD4205) as a Potent and Selective Janus Kinase 1 Inhibitor.","doi":"10.1021\/acs.jmedchem.9b01392","doi_url":"https:\/\/doi.org\/10.1021\/acs.jmedchem.9b01392","pmid":"32297743","pmid_url":"https:\/\/pubmed.ncbi.nlm.nih.gov\/32297743\/","year":2020,"journal":"J Med Chem","volume":"63","issue":"9","page":"4517-4527","authors":[{"first_name":"Banks E","last_name":null,"full_name":null},{"first_name":"Bebernitz G","last_name":null,"full_name":null},{"first_name":"Bell K","last_name":null,"full_name":null},{"first_name":"Borenstein CF","last_name":null,"full_name":null},{"first_name":"Chen H","last_name":null,"full_name":null},{"first_name":"Chuaqui CE","last_name":null,"full_name":null},{"first_name":"Deng N","last_name":null,"full_name":null},{"first_name":"Fawell S","last_name":null,"full_name":null},{"first_name":"Ferguson AD","last_name":null,"full_name":null},{"first_name":"Grimster NP","last_name":null,"full_name":null},{"first_name":"Kawatkar S","last_name":null,"full_name":null},{"first_name":"Kettle JG.","last_name":null,"full_name":null},{"first_name":"Lyne PD","last_name":null,"full_name":null},{"first_name":"Pei X","last_name":null,"full_name":null},{"first_name":"Peng X","last_name":null,"full_name":null},{"first_name":"Read JA","last_name":null,"full_name":null},{"first_name":"Ruston L","last_name":null,"full_name":null},{"first_name":"Su Q","last_name":null,"full_name":null},{"first_name":"Tang Z","last_name":null,"full_name":null},{"first_name":"Throner S","last_name":null,"full_name":null},{"first_name":"Vasbinder MM","last_name":null,"full_name":null},{"first_name":"Wang H","last_name":null,"full_name":null},{"first_name":"Winter-Holt J","last_name":null,"full_name":null},{"first_name":"Woessner R","last_name":null,"full_name":null},{"first_name":"Wu A","last_name":null,"full_name":null},{"first_name":"Yang W","last_name":null,"full_name":null},{"first_name":"Zinda M","last_name":null,"full_name":null}],"url":"https:\/\/molmedb.upol.cz\/api\/v1\/publications\/3494","landing_page":"https:\/\/molmedb.upol.cz\/publication\/3494","created_at":"2024-05-21T20:12:16.000000Z","updated_at":null}}