{"data":{"id":3426,"citation":"Beaulieu PL, Bolger G, Deon D, Duplessis M, Fazal G, Gagnon A, Garneau M, LaPlante S, Stammers T, Kukolj G, Duan J.: Multi-parameter optimization of aza-follow-ups to BI 207524, a thumb pocket 1 HCV NS5B polymerase inhibitor. Part 2: Impact of lipophilicity on promiscuity and in vivo toxicity. Bioorg Med Chem Lett, Volume 25 (5), 2015","title":"Multi-parameter optimization of aza-follow-ups to BI 207524, a thumb pocket 1 HCV NS5B polymerase inhibitor. Part 2: Impact of lipophilicity on promiscuity and in vivo toxicity.","doi":"10.1016\/j.bmcl.2014.12.078","doi_url":"https:\/\/doi.org\/10.1016\/j.bmcl.2014.12.078","pmid":"25599836","pmid_url":"https:\/\/pubmed.ncbi.nlm.nih.gov\/25599836\/","year":2015,"journal":"Bioorg Med Chem Lett","volume":"25","issue":"5","page":"1140-1145","authors":[{"first_name":"Beaulieu PL","last_name":null,"full_name":null},{"first_name":"Bolger G","last_name":null,"full_name":null},{"first_name":"Deon D","last_name":null,"full_name":null},{"first_name":"Duan J.","last_name":null,"full_name":null},{"first_name":"Duplessis M","last_name":null,"full_name":null},{"first_name":"Fazal G","last_name":null,"full_name":null},{"first_name":"Gagnon A","last_name":null,"full_name":null},{"first_name":"Garneau M","last_name":null,"full_name":null},{"first_name":"Kukolj G","last_name":null,"full_name":null},{"first_name":"LaPlante S","last_name":null,"full_name":null},{"first_name":"Stammers T","last_name":null,"full_name":null}],"url":"https:\/\/molmedb.upol.cz\/api\/v1\/publications\/3426","landing_page":"https:\/\/molmedb.upol.cz\/publication\/3426","created_at":"2024-05-21T20:12:03.000000Z","updated_at":null}}