{"data":{"id":3409,"citation":"Langston SP, Grossman S, England D, Afroze R, Bence N, Bowman D, Bump N, Chau R, Chuang BC, Claiborne C, Cohen L, Connolly K, Duffey M, Durvasula N, Freeze S, Gallery M, Galvin K, Gaulin J, Gershman R, Greenspan P, Grieves J, Guo J, Gulavita N, Hailu S, He X, Hoar K, Hu Y, Hu Z, Ito M, Kim MS, Lane SW, Lok D, Lublinsky A, Mallender W, McIntyre C, Minissale J, Mizutani H, Mizutani M, Molchinova N, Ono K, Patil A, Qian M, Riceberg J, Shindi V, Sintchak MD, Song K, Soucy T, Wang Y, Xu H, Yang X, Zawadzka A, Zhang J, Pulukuri SM.: Discovery of TAK-981, a First-in-Class Inhibitor of SUMO-Activating Enzyme for the Treatment of Cancer. J Med Chem, Volume 64 (5), 2021","title":"Discovery of TAK-981, a First-in-Class Inhibitor of SUMO-Activating Enzyme for the Treatment of Cancer.","doi":"10.1021\/acs.jmedchem.0c01491","doi_url":"https:\/\/doi.org\/10.1021\/acs.jmedchem.0c01491","pmid":"33631934","pmid_url":"https:\/\/pubmed.ncbi.nlm.nih.gov\/33631934\/","year":2021,"journal":"J Med Chem","volume":"64","issue":"5","page":"2501-2520","authors":[{"first_name":"Afroze R","last_name":null,"full_name":null},{"first_name":"Bence N","last_name":null,"full_name":null},{"first_name":"Bowman D","last_name":null,"full_name":null},{"first_name":"Bump N","last_name":null,"full_name":null},{"first_name":"Chau R","last_name":null,"full_name":null},{"first_name":"Chuang BC","last_name":null,"full_name":null},{"first_name":"Claiborne C","last_name":null,"full_name":null},{"first_name":"Cohen L","last_name":null,"full_name":null},{"first_name":"Connolly K","last_name":null,"full_name":null},{"first_name":"Duffey M","last_name":null,"full_name":null},{"first_name":"Durvasula N","last_name":null,"full_name":null},{"first_name":"England D","last_name":null,"full_name":null},{"first_name":"Freeze S","last_name":null,"full_name":null},{"first_name":"Gallery M","last_name":null,"full_name":null},{"first_name":"Galvin K","last_name":null,"full_name":null},{"first_name":"Gaulin J","last_name":null,"full_name":null},{"first_name":"Gershman R","last_name":null,"full_name":null},{"first_name":"Greenspan P","last_name":null,"full_name":null},{"first_name":"Grieves J","last_name":null,"full_name":null},{"first_name":"Grossman S","last_name":null,"full_name":null},{"first_name":"Gulavita N","last_name":null,"full_name":null},{"first_name":"Guo J","last_name":null,"full_name":null},{"first_name":"Hailu S","last_name":null,"full_name":null},{"first_name":"He X","last_name":null,"full_name":null},{"first_name":"Hoar K","last_name":null,"full_name":null},{"first_name":"Hu Y","last_name":null,"full_name":null},{"first_name":"Hu Z","last_name":null,"full_name":null},{"first_name":"Ito M","last_name":null,"full_name":null},{"first_name":"Kim MS","last_name":null,"full_name":null},{"first_name":"Lane SW","last_name":null,"full_name":null},{"first_name":"Langston SP","last_name":null,"full_name":null},{"first_name":"Lok D","last_name":null,"full_name":null},{"first_name":"Lublinsky A","last_name":null,"full_name":null},{"first_name":"Mallender W","last_name":null,"full_name":null},{"first_name":"McIntyre C","last_name":null,"full_name":null},{"first_name":"Minissale J","last_name":null,"full_name":null},{"first_name":"Mizutani H","last_name":null,"full_name":null},{"first_name":"Mizutani M","last_name":null,"full_name":null},{"first_name":"Molchinova N","last_name":null,"full_name":null},{"first_name":"Ono K","last_name":null,"full_name":null},{"first_name":"Patil A","last_name":null,"full_name":null},{"first_name":"Pulukuri SM.","last_name":null,"full_name":null},{"first_name":"Qian M","last_name":null,"full_name":null},{"first_name":"Riceberg J","last_name":null,"full_name":null},{"first_name":"Shindi V","last_name":null,"full_name":null},{"first_name":"Sintchak MD","last_name":null,"full_name":null},{"first_name":"Song K","last_name":null,"full_name":null},{"first_name":"Soucy T","last_name":null,"full_name":null},{"first_name":"Wang Y","last_name":null,"full_name":null},{"first_name":"Xu H","last_name":null,"full_name":null},{"first_name":"Yang X","last_name":null,"full_name":null},{"first_name":"Zawadzka A","last_name":null,"full_name":null},{"first_name":"Zhang J","last_name":null,"full_name":null}],"url":"https:\/\/molmedb.upol.cz\/api\/v1\/publications\/3409","landing_page":"https:\/\/molmedb.upol.cz\/publication\/3409","created_at":"2024-05-21T20:11:58.000000Z","updated_at":null}}