{"data":{"id":3349,"citation":"Zhang X, Dong G, Li H, Chen W, Li J, Feng C, Gu Z, Zhu F, Zhang R, Li M, Tang W, Liu H, Xu Y.: Structure-Aided Identification and Optimization of Tetrahydro-isoquinolines as Novel PDE4 Inhibitors Leading to Discovery of an Effective Antipsoriasis Agent. J Med Chem, Volume 62 (11), 2019","title":"Structure-Aided Identification and Optimization of Tetrahydro-isoquinolines as Novel PDE4 Inhibitors Leading to Discovery of an Effective Antipsoriasis Agent.","doi":"10.1021\/acs.jmedchem.9b00518","doi_url":"https:\/\/doi.org\/10.1021\/acs.jmedchem.9b00518","pmid":"31099559","pmid_url":"https:\/\/pubmed.ncbi.nlm.nih.gov\/31099559\/","year":2019,"journal":"J Med Chem","volume":"62","issue":"11","page":"5579-5593","authors":[{"first_name":"Chen W","last_name":null,"full_name":null},{"first_name":"Dong G","last_name":null,"full_name":null},{"first_name":"Feng C","last_name":null,"full_name":null},{"first_name":"Gu Z","last_name":null,"full_name":null},{"first_name":"Li H","last_name":null,"full_name":null},{"first_name":"Li J","last_name":null,"full_name":null},{"first_name":"Li M","last_name":null,"full_name":null},{"first_name":"Liu H","last_name":null,"full_name":null},{"first_name":"Tang W","last_name":null,"full_name":null},{"first_name":"Xu Y.","last_name":null,"full_name":null},{"first_name":"Zhang R","last_name":null,"full_name":null},{"first_name":"Zhang X","last_name":null,"full_name":null},{"first_name":"Zhu F","last_name":null,"full_name":null}],"url":"https:\/\/molmedb.upol.cz\/api\/v1\/publications\/3349","landing_page":"https:\/\/molmedb.upol.cz\/publication\/3349","created_at":"2024-05-21T20:11:47.000000Z","updated_at":null}}