{"data":{"id":3276,"citation":"Goldberg FW, Finlay MRV, Ting AKT, Beattie D, Lamont GM, Fallan C, Wrigley GL, Schimpl M, Howard MR, Williamson B, Vazquez-Chantada M, Barratt DG, Davies BR, Cadogan EB, Ramos-Montoya A, Dean E.: The Discovery of 7-Methyl-2-[(7-methyl[1,2,4]triazolo[1,5-<i>a<\/i>]pyridin-6-yl)amino]-9-(tetrahydro-2<i>H<\/i>-pyran-4-yl)-7,9-dihydro-8<i>H<\/i>-purin-8-one (AZD7648), a Potent and Selective DNA-Dependent Protein Kinase (DNA-PK) Inhibitor. J Med Chem, Volume 63 (7), 2020","title":"The Discovery of 7-Methyl-2-[(7-methyl[1,2,4]triazolo[1,5-<i>a<\/i>]pyridin-6-yl)amino]-9-(tetrahydro-2<i>H<\/i>-pyran-4-yl)-7,9-dihydro-8<i>H<\/i>-purin-8-one (AZD7648), a Potent and Selective DNA-Dependent Protein Kinase (DNA-PK) Inhibitor.","doi":"10.1021\/acs.jmedchem.9b01684","doi_url":"https:\/\/doi.org\/10.1021\/acs.jmedchem.9b01684","pmid":"31851518","pmid_url":"https:\/\/pubmed.ncbi.nlm.nih.gov\/31851518\/","year":2020,"journal":"J Med Chem","volume":"63","issue":"7","page":"3461-3471","authors":[{"first_name":"Barratt DG","last_name":null,"full_name":null},{"first_name":"Beattie D","last_name":null,"full_name":null},{"first_name":"Cadogan EB","last_name":null,"full_name":null},{"first_name":"Davies BR","last_name":null,"full_name":null},{"first_name":"Dean E.","last_name":null,"full_name":null},{"first_name":"Fallan C","last_name":null,"full_name":null},{"first_name":"Finlay MRV","last_name":null,"full_name":null},{"first_name":"Goldberg FW","last_name":null,"full_name":null},{"first_name":"Howard MR","last_name":null,"full_name":null},{"first_name":"Lamont GM","last_name":null,"full_name":null},{"first_name":"Ramos-Montoya A","last_name":null,"full_name":null},{"first_name":"Schimpl M","last_name":null,"full_name":null},{"first_name":"Ting AKT","last_name":null,"full_name":null},{"first_name":"Vazquez-Chantada M","last_name":null,"full_name":null},{"first_name":"Williamson B","last_name":null,"full_name":null},{"first_name":"Wrigley GL","last_name":null,"full_name":null}],"url":"https:\/\/molmedb.upol.cz\/api\/v1\/publications\/3276","landing_page":"https:\/\/molmedb.upol.cz\/publication\/3276","created_at":"2024-05-21T20:11:32.000000Z","updated_at":null}}