{"data":{"id":3267,"citation":"Labadie SS, Li J, Blake RA, Chang JH, Goodacre S, Hartman SJ, Liang W, Kiefer JR, Kleinheinz T, Lai T, Liao J, Ortwine DF, Mody V, Ray NC, Roussel F, Vinogradova M, Yeap SK, Zhang B, Zheng X, Zbieg JR, Liang J, Wang X.: Discovery of a C-8 hydroxychromene as a potent degrader of estrogen receptor alpha with improved rat oral exposure over GDC-0927. Bioorg Med Chem Lett, Volume 29 (16), 2019","title":"Discovery of a C-8 hydroxychromene as a potent degrader of estrogen receptor alpha with improved rat oral exposure over GDC-0927.","doi":"10.1016\/j.bmcl.2019.07.013","doi_url":"https:\/\/doi.org\/10.1016\/j.bmcl.2019.07.013","pmid":"31311734","pmid_url":"https:\/\/pubmed.ncbi.nlm.nih.gov\/31311734\/","year":2019,"journal":"Bioorg Med Chem Lett","volume":"29","issue":"16","page":"2090-2093","authors":[{"first_name":"Blake RA","last_name":null,"full_name":null},{"first_name":"Chang JH","last_name":null,"full_name":null},{"first_name":"Goodacre S","last_name":null,"full_name":null},{"first_name":"Hartman SJ","last_name":null,"full_name":null},{"first_name":"Kiefer JR","last_name":null,"full_name":null},{"first_name":"Kleinheinz T","last_name":null,"full_name":null},{"first_name":"Labadie SS","last_name":null,"full_name":null},{"first_name":"Lai T","last_name":null,"full_name":null},{"first_name":"Li J","last_name":null,"full_name":null},{"first_name":"Liang J","last_name":null,"full_name":null},{"first_name":"Liang W","last_name":null,"full_name":null},{"first_name":"Liao J","last_name":null,"full_name":null},{"first_name":"Mody V","last_name":null,"full_name":null},{"first_name":"Ortwine DF","last_name":null,"full_name":null},{"first_name":"Ray NC","last_name":null,"full_name":null},{"first_name":"Roussel F","last_name":null,"full_name":null},{"first_name":"Vinogradova M","last_name":null,"full_name":null},{"first_name":"Wang X.","last_name":null,"full_name":null},{"first_name":"Yeap SK","last_name":null,"full_name":null},{"first_name":"Zbieg JR","last_name":null,"full_name":null},{"first_name":"Zhang B","last_name":null,"full_name":null},{"first_name":"Zheng X","last_name":null,"full_name":null}],"url":"https:\/\/molmedb.upol.cz\/api\/v1\/publications\/3267","landing_page":"https:\/\/molmedb.upol.cz\/publication\/3267","created_at":"2024-05-21T09:16:37.000000Z","updated_at":null}}