{"data":{"id":3266,"citation":"Kung PP, Rui E, Bergqvist S, Bingham P, Braganza J, Collins M, Cui M, Diehl W, Dinh D, Fan C, Fantin VR, Gukasyan HJ, Hu W, Huang B, Kephart S, Krivacic C, Kumpf RA, Li G, Maegley KA, McAlpine I, Nguyen L, Ninkovic S, Ornelas M, Ryskin M, Scales S, Sutton S, Tatlock J, Verhelle D, Wang F, Wells P, Wythes M, Yamazaki S, Yip B, Yu X, Zehnder L, Zhang WG, Rollins RA, Edwards M.: Design and Synthesis of Pyridone-Containing 3,4-Dihydroisoquinoline-1(2H)-ones as a Novel Class of Enhancer of Zeste Homolog 2 (EZH2) Inhibitors. J Med Chem, Volume 59 (18), 2016","title":"Design and Synthesis of Pyridone-Containing 3,4-Dihydroisoquinoline-1(2H)-ones as a Novel Class of Enhancer of Zeste Homolog 2 (EZH2) Inhibitors.","doi":"10.1021\/acs.jmedchem.6b00515","doi_url":"https:\/\/doi.org\/10.1021\/acs.jmedchem.6b00515","pmid":"27512831","pmid_url":"https:\/\/pubmed.ncbi.nlm.nih.gov\/27512831\/","year":2016,"journal":"J Med Chem","volume":"59","issue":"18","page":"8306-8325","authors":[{"first_name":"Bergqvist S","last_name":null,"full_name":null},{"first_name":"Bingham P","last_name":null,"full_name":null},{"first_name":"Braganza J","last_name":null,"full_name":null},{"first_name":"Collins M","last_name":null,"full_name":null},{"first_name":"Cui M","last_name":null,"full_name":null},{"first_name":"Diehl W","last_name":null,"full_name":null},{"first_name":"Dinh D","last_name":null,"full_name":null},{"first_name":"Edwards M.","last_name":null,"full_name":null},{"first_name":"Fan C","last_name":null,"full_name":null},{"first_name":"Fantin VR","last_name":null,"full_name":null},{"first_name":"Gukasyan HJ","last_name":null,"full_name":null},{"first_name":"Hu W","last_name":null,"full_name":null},{"first_name":"Huang B","last_name":null,"full_name":null},{"first_name":"Kephart S","last_name":null,"full_name":null},{"first_name":"Krivacic C","last_name":null,"full_name":null},{"first_name":"Kumpf RA","last_name":null,"full_name":null},{"first_name":"Kung PP","last_name":null,"full_name":null},{"first_name":"Li G","last_name":null,"full_name":null},{"first_name":"Maegley KA","last_name":null,"full_name":null},{"first_name":"McAlpine I","last_name":null,"full_name":null},{"first_name":"Nguyen L","last_name":null,"full_name":null},{"first_name":"Ninkovic S","last_name":null,"full_name":null},{"first_name":"Ornelas M","last_name":null,"full_name":null},{"first_name":"Rollins RA","last_name":null,"full_name":null},{"first_name":"Rui E","last_name":null,"full_name":null},{"first_name":"Ryskin M","last_name":null,"full_name":null},{"first_name":"Scales S","last_name":null,"full_name":null},{"first_name":"Sutton S","last_name":null,"full_name":null},{"first_name":"Tatlock J","last_name":null,"full_name":null},{"first_name":"Verhelle D","last_name":null,"full_name":null},{"first_name":"Wang F","last_name":null,"full_name":null},{"first_name":"Wells P","last_name":null,"full_name":null},{"first_name":"Wythes M","last_name":null,"full_name":null},{"first_name":"Yamazaki S","last_name":null,"full_name":null},{"first_name":"Yip B","last_name":null,"full_name":null},{"first_name":"Yu X","last_name":null,"full_name":null},{"first_name":"Zehnder L","last_name":null,"full_name":null},{"first_name":"Zhang WG","last_name":null,"full_name":null}],"url":"https:\/\/molmedb.upol.cz\/api\/v1\/publications\/3266","landing_page":"https:\/\/molmedb.upol.cz\/publication\/3266","created_at":"2024-05-21T09:16:37.000000Z","updated_at":null}}