{"data":{"id":3245,"citation":"Fauber BP, Ren\u00e9 O, de Leon Boenig G, Burton B, Deng Y, Eidenschenk C, Everett C, Gobbi A, Hymowitz SG, Johnson AR, La H, Liimatta M, Lockey P, Norman M, Ouyang W, Wang W, Wong H.: Reduction in lipophilicity improved the solubility, plasma-protein binding, and permeability of tertiary sulfonamide RORc inverse agonists. Bioorg Med Chem Lett, Volume 24 (16), 2014","title":"Reduction in lipophilicity improved the solubility, plasma-protein binding, and permeability of tertiary sulfonamide RORc inverse agonists.","doi":"10.1016\/j.bmcl.2014.06.048","doi_url":"https:\/\/doi.org\/10.1016\/j.bmcl.2014.06.048","pmid":"25017032","pmid_url":"https:\/\/pubmed.ncbi.nlm.nih.gov\/25017032\/","year":2014,"journal":"Bioorg Med Chem Lett","volume":"24","issue":"16","page":"3891-3897","authors":[{"first_name":"Burton B","last_name":null,"full_name":null},{"first_name":"de Leon Boenig G","last_name":null,"full_name":null},{"first_name":"Deng Y","last_name":null,"full_name":null},{"first_name":"Eidenschenk C","last_name":null,"full_name":null},{"first_name":"Everett C","last_name":null,"full_name":null},{"first_name":"Fauber BP","last_name":null,"full_name":null},{"first_name":"Gobbi A","last_name":null,"full_name":null},{"first_name":"Hymowitz SG","last_name":null,"full_name":null},{"first_name":"Johnson AR","last_name":null,"full_name":null},{"first_name":"La H","last_name":null,"full_name":null},{"first_name":"Liimatta M","last_name":null,"full_name":null},{"first_name":"Lockey P","last_name":null,"full_name":null},{"first_name":"Norman M","last_name":null,"full_name":null},{"first_name":"Ouyang W","last_name":null,"full_name":null},{"first_name":"Ren\u00e9 O","last_name":null,"full_name":null},{"first_name":"Wang W","last_name":null,"full_name":null},{"first_name":"Wong H.","last_name":null,"full_name":null}],"url":"https:\/\/molmedb.upol.cz\/api\/v1\/publications\/3245","landing_page":"https:\/\/molmedb.upol.cz\/publication\/3245","created_at":"2024-05-21T09:16:31.000000Z","updated_at":null}}