{"data":{"id":3232,"citation":"Sifferlen T, Boller A, Chardonneau A, Cottreel E, Hoecker J, Aissaoui H, Williams JT, Brotschi C, Heidmann B, Siegrist R, Gatfield J, Treiber A, Brisbare-Roch C, Jenck F, Boss C.: Discovery of substituted lactams as novel dual orexin receptor antagonists. Synthesis, preliminary structure-activity relationship studies and efforts towards improved metabolic stability and pharmacokinetic properties. Part 1. Bioorg Med Chem Lett, Volume 24 (4), 2014","title":"Discovery of substituted lactams as novel dual orexin receptor antagonists. Synthesis, preliminary structure-activity relationship studies and efforts towards improved metabolic stability and pharmacokinetic properties. Part 1.","doi":"10.1016\/j.bmcl.2013.12.092","doi_url":"https:\/\/doi.org\/10.1016\/j.bmcl.2013.12.092","pmid":"24447850","pmid_url":"https:\/\/pubmed.ncbi.nlm.nih.gov\/24447850\/","year":2014,"journal":"Bioorg Med Chem Lett","volume":"24","issue":"4","page":"1201-1208","authors":[{"first_name":"Aissaoui H","last_name":null,"full_name":null},{"first_name":"Boller A","last_name":null,"full_name":null},{"first_name":"Boss C.","last_name":null,"full_name":null},{"first_name":"Brisbare-Roch C","last_name":null,"full_name":null},{"first_name":"Brotschi C","last_name":null,"full_name":null},{"first_name":"Chardonneau A","last_name":null,"full_name":null},{"first_name":"Cottreel E","last_name":null,"full_name":null},{"first_name":"Gatfield J","last_name":null,"full_name":null},{"first_name":"Heidmann B","last_name":null,"full_name":null},{"first_name":"Hoecker J","last_name":null,"full_name":null},{"first_name":"Jenck F","last_name":null,"full_name":null},{"first_name":"Siegrist R","last_name":null,"full_name":null},{"first_name":"Sifferlen T","last_name":null,"full_name":null},{"first_name":"Treiber A","last_name":null,"full_name":null},{"first_name":"Williams JT","last_name":null,"full_name":null}],"url":"https:\/\/molmedb.upol.cz\/api\/v1\/publications\/3232","landing_page":"https:\/\/molmedb.upol.cz\/publication\/3232","created_at":"2024-05-21T09:16:28.000000Z","updated_at":null}}