{"data":{"id":3185,"citation":"Liang J, van Abbema A, Balazs M, Barrett K, Berezhkovsky L, Blair W, Chang C, Delarosa D, DeVoss J, Driscoll J, Eigenbrot C, Ghilardi N, Gibbons P, Halladay J, Johnson A, Kohli PB, Lai Y, Liu Y, Lyssikatos J, Mantik P, Menghrajani K, Murray J, Peng I, Sambrone A, Shia S, Shin Y, Smith J, Sohn S, Tsui V, Ultsch M, Wu LC, Xiao Y, Yang W, Young J, Zhang B, Zhu BY, Magnuson S.: Lead optimization of a 4-aminopyridine benzamide scaffold to identify potent, selective, and orally bioavailable TYK2 inhibitors. J Med Chem, Volume 56 (11), 2013","title":"Lead optimization of a 4-aminopyridine benzamide scaffold to identify potent, selective, and orally bioavailable TYK2 inhibitors.","doi":"10.1021\/jm400266t","doi_url":"https:\/\/doi.org\/10.1021\/jm400266t","pmid":"23668484","pmid_url":"https:\/\/pubmed.ncbi.nlm.nih.gov\/23668484\/","year":2013,"journal":"J Med Chem","volume":"56","issue":"11","page":"4521-4536","authors":[{"first_name":"Balazs M","last_name":null,"full_name":null},{"first_name":"Barrett K","last_name":null,"full_name":null},{"first_name":"Berezhkovsky L","last_name":null,"full_name":null},{"first_name":"Blair W","last_name":null,"full_name":null},{"first_name":"Chang C","last_name":null,"full_name":null},{"first_name":"Delarosa D","last_name":null,"full_name":null},{"first_name":"DeVoss J","last_name":null,"full_name":null},{"first_name":"Driscoll J","last_name":null,"full_name":null},{"first_name":"Eigenbrot C","last_name":null,"full_name":null},{"first_name":"Ghilardi N","last_name":null,"full_name":null},{"first_name":"Gibbons P","last_name":null,"full_name":null},{"first_name":"Halladay J","last_name":null,"full_name":null},{"first_name":"Johnson A","last_name":null,"full_name":null},{"first_name":"Kohli PB","last_name":null,"full_name":null},{"first_name":"Lai Y","last_name":null,"full_name":null},{"first_name":"Liang J","last_name":null,"full_name":null},{"first_name":"Liu Y","last_name":null,"full_name":null},{"first_name":"Lyssikatos J","last_name":null,"full_name":null},{"first_name":"Magnuson S.","last_name":null,"full_name":null},{"first_name":"Mantik P","last_name":null,"full_name":null},{"first_name":"Menghrajani K","last_name":null,"full_name":null},{"first_name":"Murray J","last_name":null,"full_name":null},{"first_name":"Peng I","last_name":null,"full_name":null},{"first_name":"Sambrone A","last_name":null,"full_name":null},{"first_name":"Shia S","last_name":null,"full_name":null},{"first_name":"Shin Y","last_name":null,"full_name":null},{"first_name":"Smith J","last_name":null,"full_name":null},{"first_name":"Sohn S","last_name":null,"full_name":null},{"first_name":"Tsui V","last_name":null,"full_name":null},{"first_name":"Ultsch M","last_name":null,"full_name":null},{"first_name":"van Abbema A","last_name":null,"full_name":null},{"first_name":"Wu LC","last_name":null,"full_name":null},{"first_name":"Xiao Y","last_name":null,"full_name":null},{"first_name":"Yang W","last_name":null,"full_name":null},{"first_name":"Young J","last_name":null,"full_name":null},{"first_name":"Zhang B","last_name":null,"full_name":null},{"first_name":"Zhu BY","last_name":null,"full_name":null}],"url":"https:\/\/molmedb.upol.cz\/api\/v1\/publications\/3185","landing_page":"https:\/\/molmedb.upol.cz\/publication\/3185","created_at":"2024-05-21T09:16:15.000000Z","updated_at":null}}