{"data":{"id":3167,"citation":"Skidmore J, Heer J, Johnson CN, Norton D, Redshaw S, Sweeting J, Hurst D, Cridland A, Vesey D, Wall I, Ahmed M, Rivers D, Myatt J, Giblin G, Philpott K, Kumar U, Stevens A, Bit RA, Haynes A, Taylor S, Watson R, Witherington J, Demont E, Heightman TD.: Optimization of sphingosine-1-phosphate-1 receptor agonists: effects of acidic, basic, and zwitterionic chemotypes on pharmacokinetic and pharmacodynamic profiles. J Med Chem, Volume 57 (24), 2014","title":"Optimization of sphingosine-1-phosphate-1 receptor agonists: effects of acidic, basic, and zwitterionic chemotypes on pharmacokinetic and pharmacodynamic profiles.","doi":"10.1021\/jm5010336","doi_url":"https:\/\/doi.org\/10.1021\/jm5010336","pmid":"25431977","pmid_url":"https:\/\/pubmed.ncbi.nlm.nih.gov\/25431977\/","year":2014,"journal":"J Med Chem","volume":"57","issue":"24","page":"10424-10442","authors":[{"first_name":"Ahmed M","last_name":null,"full_name":null},{"first_name":"Bit RA","last_name":null,"full_name":null},{"first_name":"Cridland A","last_name":null,"full_name":null},{"first_name":"Demont E","last_name":null,"full_name":null},{"first_name":"Giblin G","last_name":null,"full_name":null},{"first_name":"Haynes A","last_name":null,"full_name":null},{"first_name":"Heer J","last_name":null,"full_name":null},{"first_name":"Heightman TD.","last_name":null,"full_name":null},{"first_name":"Hurst D","last_name":null,"full_name":null},{"first_name":"Johnson CN","last_name":null,"full_name":null},{"first_name":"Kumar U","last_name":null,"full_name":null},{"first_name":"Myatt J","last_name":null,"full_name":null},{"first_name":"Norton D","last_name":null,"full_name":null},{"first_name":"Philpott K","last_name":null,"full_name":null},{"first_name":"Redshaw S","last_name":null,"full_name":null},{"first_name":"Rivers D","last_name":null,"full_name":null},{"first_name":"Skidmore J","last_name":null,"full_name":null},{"first_name":"Stevens A","last_name":null,"full_name":null},{"first_name":"Sweeting J","last_name":null,"full_name":null},{"first_name":"Taylor S","last_name":null,"full_name":null},{"first_name":"Vesey D","last_name":null,"full_name":null},{"first_name":"Wall I","last_name":null,"full_name":null},{"first_name":"Watson R","last_name":null,"full_name":null},{"first_name":"Witherington J","last_name":null,"full_name":null}],"url":"https:\/\/molmedb.upol.cz\/api\/v1\/publications\/3167","landing_page":"https:\/\/molmedb.upol.cz\/publication\/3167","created_at":"2024-05-21T09:16:09.000000Z","updated_at":null}}