{"data":{"id":3152,"citation":"Helal CJ, Kang Z, Hou X, Pandit J, Chappie TA, Humphrey JM, Marr ES, Fennell KF, Chenard LK, Fox C, Schmidt CJ, Williams RD, Chapin DS, Siuciak J, Lebel L, Menniti F, Cianfrogna J, Fonseca KR, Nelson FR, O'Connor R, MacDougall M, McDowell L, Liras S.: Use of structure-based design to discover a potent, selective, in vivo active phosphodiesterase 10A inhibitor lead series for the treatment of schizophrenia. J Med Chem, Volume 54 (13), 2011","title":"Use of structure-based design to discover a potent, selective, in vivo active phosphodiesterase 10A inhibitor lead series for the treatment of schizophrenia.","doi":"10.1021\/jm2001508","doi_url":"https:\/\/doi.org\/10.1021\/jm2001508","pmid":"21650160","pmid_url":"https:\/\/pubmed.ncbi.nlm.nih.gov\/21650160\/","year":2011,"journal":"J Med Chem","volume":"54","issue":"13","page":"4536-4547","authors":[{"first_name":"Chapin DS","last_name":null,"full_name":null},{"first_name":"Chappie TA","last_name":null,"full_name":null},{"first_name":"Chenard LK","last_name":null,"full_name":null},{"first_name":"Cianfrogna J","last_name":null,"full_name":null},{"first_name":"Fennell KF","last_name":null,"full_name":null},{"first_name":"Fonseca KR","last_name":null,"full_name":null},{"first_name":"Fox C","last_name":null,"full_name":null},{"first_name":"Helal CJ","last_name":null,"full_name":null},{"first_name":"Hou X","last_name":null,"full_name":null},{"first_name":"Humphrey JM","last_name":null,"full_name":null},{"first_name":"Kang Z","last_name":null,"full_name":null},{"first_name":"Lebel L","last_name":null,"full_name":null},{"first_name":"Liras S.","last_name":null,"full_name":null},{"first_name":"MacDougall M","last_name":null,"full_name":null},{"first_name":"Marr ES","last_name":null,"full_name":null},{"first_name":"McDowell L","last_name":null,"full_name":null},{"first_name":"Menniti F","last_name":null,"full_name":null},{"first_name":"Nelson FR","last_name":null,"full_name":null},{"first_name":"O'Connor R","last_name":null,"full_name":null},{"first_name":"Pandit J","last_name":null,"full_name":null},{"first_name":"Schmidt CJ","last_name":null,"full_name":null},{"first_name":"Siuciak J","last_name":null,"full_name":null},{"first_name":"Williams RD","last_name":null,"full_name":null}],"url":"https:\/\/molmedb.upol.cz\/api\/v1\/publications\/3152","landing_page":"https:\/\/molmedb.upol.cz\/publication\/3152","created_at":"2024-05-21T09:16:06.000000Z","updated_at":null}}