{"data":{"id":3140,"citation":"Koriyama Y, Hori A, Ito H, Yonezawa S, Baba Y, Tanimoto N, Ueno T, Yamamoto S, Yamamoto T, Asada N, Morimoto K, Einaru S, Sakai K, Kanazu T, Matsuda A, Yamaguchi Y, Oguma T, Timmers M, Tritsmans L, Kusakabe KI, Kato A, Sakaguchi G.: Discovery of Atabecestat (JNJ-54861911): A Thiazine-Based \u03b2-Amyloid Precursor Protein Cleaving Enzyme 1 Inhibitor Advanced to the Phase 2b\/3 EARLY Clinical Trial. J Med Chem, Volume 64 (4), 2021","title":"Discovery of Atabecestat (JNJ-54861911): A Thiazine-Based \u03b2-Amyloid Precursor Protein Cleaving Enzyme 1 Inhibitor Advanced to the Phase 2b\/3 EARLY Clinical Trial.","doi":"10.1021\/acs.jmedchem.0c01917","doi_url":"https:\/\/doi.org\/10.1021\/acs.jmedchem.0c01917","pmid":"33588527","pmid_url":"https:\/\/pubmed.ncbi.nlm.nih.gov\/33588527\/","year":2021,"journal":"J Med Chem","volume":"64","issue":"4","page":"1873-1888","authors":[{"first_name":"Asada N","last_name":null,"full_name":null},{"first_name":"Baba Y","last_name":null,"full_name":null},{"first_name":"Einaru S","last_name":null,"full_name":null},{"first_name":"Hori A","last_name":null,"full_name":null},{"first_name":"Ito H","last_name":null,"full_name":null},{"first_name":"Kanazu T","last_name":null,"full_name":null},{"first_name":"Kato A","last_name":null,"full_name":null},{"first_name":"Koriyama Y","last_name":null,"full_name":null},{"first_name":"Kusakabe KI","last_name":null,"full_name":null},{"first_name":"Matsuda A","last_name":null,"full_name":null},{"first_name":"Morimoto K","last_name":null,"full_name":null},{"first_name":"Oguma T","last_name":null,"full_name":null},{"first_name":"Sakaguchi G.","last_name":null,"full_name":null},{"first_name":"Sakai K","last_name":null,"full_name":null},{"first_name":"Tanimoto N","last_name":null,"full_name":null},{"first_name":"Timmers M","last_name":null,"full_name":null},{"first_name":"Tritsmans L","last_name":null,"full_name":null},{"first_name":"Ueno T","last_name":null,"full_name":null},{"first_name":"Yamaguchi Y","last_name":null,"full_name":null},{"first_name":"Yamamoto S","last_name":null,"full_name":null},{"first_name":"Yamamoto T","last_name":null,"full_name":null},{"first_name":"Yonezawa S","last_name":null,"full_name":null}],"url":"https:\/\/molmedb.upol.cz\/api\/v1\/publications\/3140","landing_page":"https:\/\/molmedb.upol.cz\/publication\/3140","created_at":"2024-05-21T09:16:03.000000Z","updated_at":null}}