{"data":{"id":3137,"citation":"Betschart C, Faller M, Zink F, Hemmig R, Blank J, Vangrevelinghe E, Bourrel M, Glatthar R, Behnke D, Barker K, Heizmann A, Angst D, Nimsgern P, Jacquier S, Junt T, Zipfel G, Ruzzante G, Loetscher P, Limonta S, Hawtin S, Andre CB, Boulay T, Feifel R, Knoepfel T.: Structure-Based Optimization of a Fragment-like TLR8 Binding Screening Hit to an <i>In Vivo<\/i> Efficacious TLR7\/8 Antagonist. ACS Med Chem Lett, Volume 13 (4), 2022","title":"Structure-Based Optimization of a Fragment-like TLR8 Binding Screening Hit to an <i>In Vivo<\/i> Efficacious TLR7\/8 Antagonist.","doi":"10.1021\/acsmedchemlett.1c00696","doi_url":"https:\/\/doi.org\/10.1021\/acsmedchemlett.1c00696","pmid":"35450354","pmid_url":"https:\/\/pubmed.ncbi.nlm.nih.gov\/35450354\/","year":2022,"journal":"ACS Med Chem Lett","volume":"13","issue":"4","page":"658-664","authors":[{"first_name":"Andre CB","last_name":null,"full_name":null},{"first_name":"Angst D","last_name":null,"full_name":null},{"first_name":"Barker K","last_name":null,"full_name":null},{"first_name":"Behnke D","last_name":null,"full_name":null},{"first_name":"Betschart C","last_name":null,"full_name":null},{"first_name":"Blank J","last_name":null,"full_name":null},{"first_name":"Boulay T","last_name":null,"full_name":null},{"first_name":"Bourrel M","last_name":null,"full_name":null},{"first_name":"Faller M","last_name":null,"full_name":null},{"first_name":"Feifel R","last_name":null,"full_name":null},{"first_name":"Glatthar R","last_name":null,"full_name":null},{"first_name":"Hawtin S","last_name":null,"full_name":null},{"first_name":"Heizmann A","last_name":null,"full_name":null},{"first_name":"Hemmig R","last_name":null,"full_name":null},{"first_name":"Jacquier S","last_name":null,"full_name":null},{"first_name":"Junt T","last_name":null,"full_name":null},{"first_name":"Knoepfel T.","last_name":null,"full_name":null},{"first_name":"Limonta S","last_name":null,"full_name":null},{"first_name":"Loetscher P","last_name":null,"full_name":null},{"first_name":"Nimsgern P","last_name":null,"full_name":null},{"first_name":"Ruzzante G","last_name":null,"full_name":null},{"first_name":"Vangrevelinghe E","last_name":null,"full_name":null},{"first_name":"Zink F","last_name":null,"full_name":null},{"first_name":"Zipfel G","last_name":null,"full_name":null}],"url":"https:\/\/molmedb.upol.cz\/api\/v1\/publications\/3137","landing_page":"https:\/\/molmedb.upol.cz\/publication\/3137","created_at":"2024-05-21T09:16:02.000000Z","updated_at":null}}