{"data":{"id":3089,"citation":"Claffey MM, Helal CJ, Verhoest PR, Kang Z, Fors KS, Jung S, Zhong J, Bundesmann MW, Hou X, Lui S, Kleiman RJ, Vanase-Frawley M, Schmidt AW, Menniti F, Schmidt CJ, Hoffman WE, Hajos M, McDowell L, O'Connor RE, Macdougall-Murphy M, Fonseca KR, Becker SL, Nelson FR, Liras S.: Application of structure-based drug design and parallel chemistry to identify selective, brain penetrant, in vivo active phosphodiesterase 9A inhibitors. J Med Chem, Volume 55 (21), 2012","title":"Application of structure-based drug design and parallel chemistry to identify selective, brain penetrant, in vivo active phosphodiesterase 9A inhibitors.","doi":"10.1021\/jm3009635","doi_url":"https:\/\/doi.org\/10.1021\/jm3009635","pmid":"23025719","pmid_url":"https:\/\/pubmed.ncbi.nlm.nih.gov\/23025719\/","year":2012,"journal":"J Med Chem","volume":"55","issue":"21","page":"9055-9068","authors":[{"first_name":"Becker SL","last_name":null,"full_name":null},{"first_name":"Bundesmann MW","last_name":null,"full_name":null},{"first_name":"Claffey MM","last_name":null,"full_name":null},{"first_name":"Fonseca KR","last_name":null,"full_name":null},{"first_name":"Fors KS","last_name":null,"full_name":null},{"first_name":"Hajos M","last_name":null,"full_name":null},{"first_name":"Helal CJ","last_name":null,"full_name":null},{"first_name":"Hoffman WE","last_name":null,"full_name":null},{"first_name":"Hou X","last_name":null,"full_name":null},{"first_name":"Jung S","last_name":null,"full_name":null},{"first_name":"Kang Z","last_name":null,"full_name":null},{"first_name":"Kleiman RJ","last_name":null,"full_name":null},{"first_name":"Liras S.","last_name":null,"full_name":null},{"first_name":"Lui S","last_name":null,"full_name":null},{"first_name":"Macdougall-Murphy M","last_name":null,"full_name":null},{"first_name":"McDowell L","last_name":null,"full_name":null},{"first_name":"Menniti F","last_name":null,"full_name":null},{"first_name":"Nelson FR","last_name":null,"full_name":null},{"first_name":"O'Connor RE","last_name":null,"full_name":null},{"first_name":"Schmidt AW","last_name":null,"full_name":null},{"first_name":"Schmidt CJ","last_name":null,"full_name":null},{"first_name":"Vanase-Frawley M","last_name":null,"full_name":null},{"first_name":"Verhoest PR","last_name":null,"full_name":null},{"first_name":"Zhong J","last_name":null,"full_name":null}],"url":"https:\/\/molmedb.upol.cz\/api\/v1\/publications\/3089","landing_page":"https:\/\/molmedb.upol.cz\/publication\/3089","created_at":"2024-05-21T09:15:51.000000Z","updated_at":null}}