{"data":{"id":3080,"citation":"Down K, Amour A, Anderson NA, Barton N, Campos S, Cannons EP, Clissold C, Convery MA, Coward JJ, Doyle K, Duempelfeld B, Edwards CD, Goldsmith MD, Krause J, Mallett DN, McGonagle GA, Patel VK, Rowedder J, Rowland P, Sharpe A, Sriskantharajah S, Thomas DA, Thomson DW, Uddin S, Hamblin JN, Hessel EM.: Discovery of GSK251: A Highly Potent, Highly Selective, Orally Bioavailable Inhibitor of PI3K\u03b4 with a Novel Binding Mode. J Med Chem, Volume 64 (18), 2021","title":"Discovery of GSK251: A Highly Potent, Highly Selective, Orally Bioavailable Inhibitor of PI3K\u03b4 with a Novel Binding Mode.","doi":"10.1021\/acs.jmedchem.1c01102","doi_url":"https:\/\/doi.org\/10.1021\/acs.jmedchem.1c01102","pmid":"34510892","pmid_url":"https:\/\/pubmed.ncbi.nlm.nih.gov\/34510892\/","year":2021,"journal":"J Med Chem","volume":"64","issue":"18","page":"13780-13792","authors":[{"first_name":"Amour A","last_name":null,"full_name":null},{"first_name":"Anderson NA","last_name":null,"full_name":null},{"first_name":"Barton N","last_name":null,"full_name":null},{"first_name":"Campos S","last_name":null,"full_name":null},{"first_name":"Cannons EP","last_name":null,"full_name":null},{"first_name":"Clissold C","last_name":null,"full_name":null},{"first_name":"Convery MA","last_name":null,"full_name":null},{"first_name":"Coward JJ","last_name":null,"full_name":null},{"first_name":"Down K","last_name":null,"full_name":null},{"first_name":"Doyle K","last_name":null,"full_name":null},{"first_name":"Duempelfeld B","last_name":null,"full_name":null},{"first_name":"Edwards CD","last_name":null,"full_name":null},{"first_name":"Goldsmith MD","last_name":null,"full_name":null},{"first_name":"Hamblin JN","last_name":null,"full_name":null},{"first_name":"Hessel EM.","last_name":null,"full_name":null},{"first_name":"Krause J","last_name":null,"full_name":null},{"first_name":"Mallett DN","last_name":null,"full_name":null},{"first_name":"McGonagle GA","last_name":null,"full_name":null},{"first_name":"Patel VK","last_name":null,"full_name":null},{"first_name":"Rowedder J","last_name":null,"full_name":null},{"first_name":"Rowland P","last_name":null,"full_name":null},{"first_name":"Sharpe A","last_name":null,"full_name":null},{"first_name":"Sriskantharajah S","last_name":null,"full_name":null},{"first_name":"Thomas DA","last_name":null,"full_name":null},{"first_name":"Thomson DW","last_name":null,"full_name":null},{"first_name":"Uddin S","last_name":null,"full_name":null}],"url":"https:\/\/molmedb.upol.cz\/api\/v1\/publications\/3080","landing_page":"https:\/\/molmedb.upol.cz\/publication\/3080","created_at":"2024-05-21T09:15:49.000000Z","updated_at":null}}