{"data":{"id":3039,"citation":"Burch JD, Barrett K, Chen Y, DeVoss J, Eigenbrot C, Goldsmith R, Ismaili MH, Lau K, Lin Z, Ortwine DF, Zarrin AA, McEwan PA, Barker JJ, Ellebrandt C, Kordt D, Stein DB, Wang X, Chen Y, Hu B, Xu X, Yuen PW, Zhang Y, Pei Z.: Tetrahydroindazoles as Interleukin-2 Inducible T-Cell Kinase Inhibitors. Part II. Second-Generation Analogues with Enhanced Potency, Selectivity, and Pharmacodynamic Modulation in Vivo. J Med Chem, Volume 58 (9), 2015","title":"Tetrahydroindazoles as Interleukin-2 Inducible T-Cell Kinase Inhibitors. Part II. Second-Generation Analogues with Enhanced Potency, Selectivity, and Pharmacodynamic Modulation in Vivo.","doi":"10.1021\/jm501998m","doi_url":"https:\/\/doi.org\/10.1021\/jm501998m","pmid":"25844760","pmid_url":"https:\/\/pubmed.ncbi.nlm.nih.gov\/25844760\/","year":2015,"journal":"J Med Chem","volume":"58","issue":"9","page":"3806-3816","authors":[{"first_name":"Barker JJ","last_name":null,"full_name":null},{"first_name":"Barrett K","last_name":null,"full_name":null},{"first_name":"Burch JD","last_name":null,"full_name":null},{"first_name":"Chen Y","last_name":null,"full_name":null},{"first_name":"DeVoss J","last_name":null,"full_name":null},{"first_name":"Eigenbrot C","last_name":null,"full_name":null},{"first_name":"Ellebrandt C","last_name":null,"full_name":null},{"first_name":"Goldsmith R","last_name":null,"full_name":null},{"first_name":"Hu B","last_name":null,"full_name":null},{"first_name":"Ismaili MH","last_name":null,"full_name":null},{"first_name":"Kordt D","last_name":null,"full_name":null},{"first_name":"Lau K","last_name":null,"full_name":null},{"first_name":"Lin Z","last_name":null,"full_name":null},{"first_name":"McEwan PA","last_name":null,"full_name":null},{"first_name":"Ortwine DF","last_name":null,"full_name":null},{"first_name":"Pei Z.","last_name":null,"full_name":null},{"first_name":"Stein DB","last_name":null,"full_name":null},{"first_name":"Wang X","last_name":null,"full_name":null},{"first_name":"Xu X","last_name":null,"full_name":null},{"first_name":"Yuen PW","last_name":null,"full_name":null},{"first_name":"Zarrin AA","last_name":null,"full_name":null},{"first_name":"Zhang Y","last_name":null,"full_name":null}],"url":"https:\/\/molmedb.upol.cz\/api\/v1\/publications\/3039","landing_page":"https:\/\/molmedb.upol.cz\/publication\/3039","created_at":"2024-05-21T09:15:40.000000Z","updated_at":null}}