{"data":{"id":2938,"citation":"Rageot D, Bohnacker T, Melone A, Langlois JB, Borsari C, Hillmann P, Sele AM, Beaufils F, Zvelebil M, Hebeisen P, L\u00f6scher W, Burke J, Fabbro D, Wymann MP.: Discovery and Preclinical Characterization of 5-[4,6-Bis({3-oxa-8-azabicyclo[3.2.1]octan-8-yl})-1,3,5-triazin-2-yl]-4-(difluoromethyl)pyridin-2-amine (PQR620), a Highly Potent and Selective mTORC1\/2 Inhibitor for Cancer and Neurological Disorders. J Med Chem, Volume 61 (22), 2018","title":"Discovery and Preclinical Characterization of 5-[4,6-Bis({3-oxa-8-azabicyclo[3.2.1]octan-8-yl})-1,3,5-triazin-2-yl]-4-(difluoromethyl)pyridin-2-amine (PQR620), a Highly Potent and Selective mTORC1\/2 Inhibitor for Cancer and Neurological Disorders.","doi":"10.1021\/acs.jmedchem.8b01262","doi_url":"https:\/\/doi.org\/10.1021\/acs.jmedchem.8b01262","pmid":"30359003","pmid_url":"https:\/\/pubmed.ncbi.nlm.nih.gov\/30359003\/","year":2018,"journal":"J Med Chem","volume":"61","issue":"22","page":"10084-10105","authors":[{"first_name":"Beaufils F","last_name":null,"full_name":null},{"first_name":"Bohnacker T","last_name":null,"full_name":null},{"first_name":"Borsari C","last_name":null,"full_name":null},{"first_name":"Burke J","last_name":null,"full_name":null},{"first_name":"Fabbro D","last_name":null,"full_name":null},{"first_name":"Hebeisen P","last_name":null,"full_name":null},{"first_name":"Hillmann P","last_name":null,"full_name":null},{"first_name":"Langlois JB","last_name":null,"full_name":null},{"first_name":"L\u00f6scher W","last_name":null,"full_name":null},{"first_name":"Melone A","last_name":null,"full_name":null},{"first_name":"Rageot D","last_name":null,"full_name":null},{"first_name":"Sele AM","last_name":null,"full_name":null},{"first_name":"Wymann MP.","last_name":null,"full_name":null},{"first_name":"Zvelebil M","last_name":null,"full_name":null}],"url":"https:\/\/molmedb.upol.cz\/api\/v1\/publications\/2938","landing_page":"https:\/\/molmedb.upol.cz\/publication\/2938","created_at":"2023-06-23T15:10:17.000000Z","updated_at":null}}