{"data":{"id":2931,"citation":"Soares P, Gadd MS, Frost J, Galdeano C, Ellis L, Epemolu O, Rocha S, Read KD, Ciulli A.: Group-Based Optimization of Potent and Cell-Active Inhibitors of the von Hippel-Lindau (VHL) E3 Ubiquitin Ligase: Structure-Activity Relationships Leading to the Chemical Probe (2S,4R)-1-((S)-2-(1-Cyanocyclopropanecarboxamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide (VH298). J Med Chem, Volume 61 (2), 2018","title":"Group-Based Optimization of Potent and Cell-Active Inhibitors of the von Hippel-Lindau (VHL) E3 Ubiquitin Ligase: Structure-Activity Relationships Leading to the Chemical Probe (2S,4R)-1-((S)-2-(1-Cyanocyclopropanecarboxamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide (VH298).","doi":"10.1021\/acs.jmedchem.7b00675","doi_url":"https:\/\/doi.org\/10.1021\/acs.jmedchem.7b00675","pmid":"28853884","pmid_url":"https:\/\/pubmed.ncbi.nlm.nih.gov\/28853884\/","year":2018,"journal":"J Med Chem","volume":"61","issue":"2","page":"599-618","authors":[{"first_name":"Ciulli A.","last_name":null,"full_name":null},{"first_name":"Ellis L","last_name":null,"full_name":null},{"first_name":"Epemolu O","last_name":null,"full_name":null},{"first_name":"Frost J","last_name":null,"full_name":null},{"first_name":"Gadd MS","last_name":null,"full_name":null},{"first_name":"Galdeano C","last_name":null,"full_name":null},{"first_name":"Read KD","last_name":null,"full_name":null},{"first_name":"Rocha S","last_name":null,"full_name":null},{"first_name":"Soares P","last_name":null,"full_name":null}],"url":"https:\/\/molmedb.upol.cz\/api\/v1\/publications\/2931","landing_page":"https:\/\/molmedb.upol.cz\/publication\/2931","created_at":"2023-06-23T15:10:16.000000Z","updated_at":null}}