{"data":{"id":2837,"citation":"Papeo G, Posteri H, Borghi D, Busel AA, Caprera F, Casale E, Ciomei M, Cirla A, Corti E, D'Anello M, Fasolini M, Forte B, Galvani A, Isacchi A, Khvat A, Krasavin MY, Lupi R, Orsini P, Perego R, Pesenti E, Pezzetta D, Rainoldi S, Riccardi-Sirtori F, Scolaro A, Sola F, Zuccotto F, Felder ER, Donati D, Montagnoli A.: Discovery of 2-[1-(4,4-Difluorocyclohexyl)piperidin-4-yl]-6-fluoro-3-oxo-2,3-dihydro-1H-isoindole-4-carboxamide (NMS-P118): A Potent, Orally Available, and Highly Selective PARP-1 Inhibitor for Cancer Therapy. J Med Chem, Volume 58 (17), 2015","title":"Discovery of 2-[1-(4,4-Difluorocyclohexyl)piperidin-4-yl]-6-fluoro-3-oxo-2,3-dihydro-1H-isoindole-4-carboxamide (NMS-P118): A Potent, Orally Available, and Highly Selective PARP-1 Inhibitor for Cancer Therapy.","doi":"10.1021\/acs.jmedchem.5b00680","doi_url":"https:\/\/doi.org\/10.1021\/acs.jmedchem.5b00680","pmid":"26222319","pmid_url":"https:\/\/pubmed.ncbi.nlm.nih.gov\/26222319\/","year":2015,"journal":"J Med Chem","volume":"58","issue":"17","page":"6875-6898","authors":[{"first_name":"Borghi D","last_name":null,"full_name":null},{"first_name":"Busel AA","last_name":null,"full_name":null},{"first_name":"Caprera F","last_name":null,"full_name":null},{"first_name":"Casale E","last_name":null,"full_name":null},{"first_name":"Ciomei M","last_name":null,"full_name":null},{"first_name":"Cirla A","last_name":null,"full_name":null},{"first_name":"Corti E","last_name":null,"full_name":null},{"first_name":"D'Anello M","last_name":null,"full_name":null},{"first_name":"Donati D","last_name":null,"full_name":null},{"first_name":"Fasolini M","last_name":null,"full_name":null},{"first_name":"Felder ER","last_name":null,"full_name":null},{"first_name":"Forte B","last_name":null,"full_name":null},{"first_name":"Galvani A","last_name":null,"full_name":null},{"first_name":"Isacchi A","last_name":null,"full_name":null},{"first_name":"Khvat A","last_name":null,"full_name":null},{"first_name":"Krasavin MY","last_name":null,"full_name":null},{"first_name":"Lupi R","last_name":null,"full_name":null},{"first_name":"Montagnoli A.","last_name":null,"full_name":null},{"first_name":"Orsini P","last_name":null,"full_name":null},{"first_name":"Papeo G","last_name":null,"full_name":null},{"first_name":"Perego R","last_name":null,"full_name":null},{"first_name":"Pesenti E","last_name":null,"full_name":null},{"first_name":"Pezzetta D","last_name":null,"full_name":null},{"first_name":"Posteri H","last_name":null,"full_name":null},{"first_name":"Rainoldi S","last_name":null,"full_name":null},{"first_name":"Riccardi-Sirtori F","last_name":null,"full_name":null},{"first_name":"Scolaro A","last_name":null,"full_name":null},{"first_name":"Sola F","last_name":null,"full_name":null},{"first_name":"Zuccotto F","last_name":null,"full_name":null}],"url":"https:\/\/molmedb.upol.cz\/api\/v1\/publications\/2837","landing_page":"https:\/\/molmedb.upol.cz\/publication\/2837","created_at":"2023-06-23T15:09:54.000000Z","updated_at":null}}