{"data":{"id":2823,"citation":"Storer RI, Brennan PE, Brown AD, Bungay PJ, Conlon KM, Corbett MS, DePianta RP, Fish PV, Heifetz A, Ho DK, Jessiman AS, McMurray G, de Oliveira CA, Roberts LR, Root JA, Shanmugasundaram V, Shapiro MJ, Skerten M, Westbrook D, Wheeler S, Whitlock GA, Wright J.: Multiparameter optimization in CNS drug discovery: design of pyrimido[4,5-d]azepines as potent 5-hydroxytryptamine 2C (5-HT\u2082C) receptor agonists with exquisite functional selectivity over 5-HT\u2082A and 5-HT\u2082B receptors. J Med Chem, Volume 57 (12), 2014","title":"Multiparameter optimization in CNS drug discovery: design of pyrimido[4,5-d]azepines as potent 5-hydroxytryptamine 2C (5-HT\u2082C) receptor agonists with exquisite functional selectivity over 5-HT\u2082A and 5-HT\u2082B receptors.","doi":"10.1021\/jm5003292","doi_url":"https:\/\/doi.org\/10.1021\/jm5003292","pmid":"24878222","pmid_url":"https:\/\/pubmed.ncbi.nlm.nih.gov\/24878222\/","year":2014,"journal":"J Med Chem","volume":"57","issue":"12","page":"5258-5269","authors":[{"first_name":"Brennan PE","last_name":null,"full_name":null},{"first_name":"Brown AD","last_name":null,"full_name":null},{"first_name":"Bungay PJ","last_name":null,"full_name":null},{"first_name":"Conlon KM","last_name":null,"full_name":null},{"first_name":"Corbett MS","last_name":null,"full_name":null},{"first_name":"de Oliveira CA","last_name":null,"full_name":null},{"first_name":"DePianta RP","last_name":null,"full_name":null},{"first_name":"Fish PV","last_name":null,"full_name":null},{"first_name":"Heifetz A","last_name":null,"full_name":null},{"first_name":"Ho DK","last_name":null,"full_name":null},{"first_name":"Jessiman AS","last_name":null,"full_name":null},{"first_name":"McMurray G","last_name":null,"full_name":null},{"first_name":"Roberts LR","last_name":null,"full_name":null},{"first_name":"Root JA","last_name":null,"full_name":null},{"first_name":"Shanmugasundaram V","last_name":null,"full_name":null},{"first_name":"Shapiro MJ","last_name":null,"full_name":null},{"first_name":"Skerten M","last_name":null,"full_name":null},{"first_name":"Storer RI","last_name":null,"full_name":null},{"first_name":"Westbrook D","last_name":null,"full_name":null},{"first_name":"Wheeler S","last_name":null,"full_name":null},{"first_name":"Whitlock GA","last_name":null,"full_name":null},{"first_name":"Wright J.","last_name":null,"full_name":null}],"url":"https:\/\/molmedb.upol.cz\/api\/v1\/publications\/2823","landing_page":"https:\/\/molmedb.upol.cz\/publication\/2823","created_at":"2023-06-23T15:09:52.000000Z","updated_at":null}}