{"data":{"id":2755,"citation":"Shirai F, Mizutani A, Yashiroda Y, Tsumura T, Kano Y, Muramatsu Y, Chikada T, Yuki H, Niwa H, Sato S, Washizuka K, Koda Y, Mazaki Y, Jang MK, Yoshida H, Nagamori A, Okue M, Watanabe T, Kitamura K, Shitara E, Honma T, Umehara T, Shirouzu M, Fukami T, Seimiya H, Yoshida M, Koyama H.: Design and Discovery of an Orally Efficacious Spiroindolinone-Based Tankyrase Inhibitor for the Treatment of Colon Cancer. J Med Chem, Volume 63 (8), 2020","title":"Design and Discovery of an Orally Efficacious Spiroindolinone-Based Tankyrase Inhibitor for the Treatment of Colon Cancer.","doi":"10.1021\/acs.jmedchem.0c00045","doi_url":"https:\/\/doi.org\/10.1021\/acs.jmedchem.0c00045","pmid":"32202790","pmid_url":"https:\/\/pubmed.ncbi.nlm.nih.gov\/32202790\/","year":2020,"journal":"J Med Chem","volume":"63","issue":"8","page":"4183-4204","authors":[{"first_name":"Chikada T","last_name":null,"full_name":null},{"first_name":"Fukami T","last_name":null,"full_name":null},{"first_name":"Honma T","last_name":null,"full_name":null},{"first_name":"Jang MK","last_name":null,"full_name":null},{"first_name":"Kano Y","last_name":null,"full_name":null},{"first_name":"Kitamura K","last_name":null,"full_name":null},{"first_name":"Koda Y","last_name":null,"full_name":null},{"first_name":"Koyama H.","last_name":null,"full_name":null},{"first_name":"Mazaki Y","last_name":null,"full_name":null},{"first_name":"Mizutani A","last_name":null,"full_name":null},{"first_name":"Muramatsu Y","last_name":null,"full_name":null},{"first_name":"Nagamori A","last_name":null,"full_name":null},{"first_name":"Niwa H","last_name":null,"full_name":null},{"first_name":"Okue M","last_name":null,"full_name":null},{"first_name":"Sato S","last_name":null,"full_name":null},{"first_name":"Seimiya H","last_name":null,"full_name":null},{"first_name":"Shirai F","last_name":null,"full_name":null},{"first_name":"Shirouzu M","last_name":null,"full_name":null},{"first_name":"Shitara E","last_name":null,"full_name":null},{"first_name":"Tsumura T","last_name":null,"full_name":null},{"first_name":"Umehara T","last_name":null,"full_name":null},{"first_name":"Washizuka K","last_name":null,"full_name":null},{"first_name":"Watanabe T","last_name":null,"full_name":null},{"first_name":"Yashiroda Y","last_name":null,"full_name":null},{"first_name":"Yoshida H","last_name":null,"full_name":null},{"first_name":"Yoshida M","last_name":null,"full_name":null},{"first_name":"Yuki H","last_name":null,"full_name":null}],"url":"https:\/\/molmedb.upol.cz\/api\/v1\/publications\/2755","landing_page":"https:\/\/molmedb.upol.cz\/publication\/2755","created_at":"2023-06-23T15:09:36.000000Z","updated_at":null}}