{"data":{"id":2520,"citation":"Tokuhara H, Imaeda Y, Fukase Y, Iwanaga K, Taya N, Watanabe K, Kanagawa R, Matsuda K, Kajimoto Y, Kusumoto K, Kondo M, Snell G, Behnke CA, Kuroita T.: Discovery of benzimidazole derivatives as orally active renin inhibitors: Optimization of 3,5-disubstituted piperidine to improve pharmacokinetic profile. Bioorg Med Chem, Volume 26 (12), 2018","title":"Discovery of benzimidazole derivatives as orally active renin inhibitors: Optimization of 3,5-disubstituted piperidine to improve pharmacokinetic profile.","doi":"10.1016\/j.bmc.2018.04.051","doi_url":"https:\/\/doi.org\/10.1016\/j.bmc.2018.04.051","pmid":"29754833","pmid_url":"https:\/\/pubmed.ncbi.nlm.nih.gov\/29754833\/","year":2018,"journal":"Bioorg Med Chem","volume":"26","issue":"12","page":"3261-3286","authors":[{"first_name":"Behnke CA","last_name":null,"full_name":null},{"first_name":"Fukase Y","last_name":null,"full_name":null},{"first_name":"Imaeda Y","last_name":null,"full_name":null},{"first_name":"Iwanaga K","last_name":null,"full_name":null},{"first_name":"Kajimoto Y","last_name":null,"full_name":null},{"first_name":"Kanagawa R","last_name":null,"full_name":null},{"first_name":"Kondo M","last_name":null,"full_name":null},{"first_name":"Kuroita T.","last_name":null,"full_name":null},{"first_name":"Kusumoto K","last_name":null,"full_name":null},{"first_name":"Matsuda K","last_name":null,"full_name":null},{"first_name":"Snell G","last_name":null,"full_name":null},{"first_name":"Taya N","last_name":null,"full_name":null},{"first_name":"Tokuhara H","last_name":null,"full_name":null},{"first_name":"Watanabe K","last_name":null,"full_name":null}],"url":"https:\/\/molmedb.upol.cz\/api\/v1\/publications\/2520","landing_page":"https:\/\/molmedb.upol.cz\/publication\/2520","created_at":"2023-06-23T15:08:41.000000Z","updated_at":null}}