{"data":{"id":2498,"citation":"Sakauchi N, Kohara Y, Sato A, Suzaki T, Imai Y, Okabe Y, Imai S, Saikawa R, Nagabukuro H, Kuno H, Fujita H, Kamo I, Yoshida M.: Discovery of 5-Chloro-1-(5-chloro-2-(methylsulfonyl)benzyl)-2-imino-1,2-dihydropyridine-3-carboxamide (TAK-259) as a Novel, Selective, and Orally Active \u03b11D Adrenoceptor Antagonist with Antiurinary Frequency Effects: Reducing Human Ether-a-go-go-Related Gene (hERG) Liabilities. J Med Chem, Volume 59 (7), 2016","title":"Discovery of 5-Chloro-1-(5-chloro-2-(methylsulfonyl)benzyl)-2-imino-1,2-dihydropyridine-3-carboxamide (TAK-259) as a Novel, Selective, and Orally Active \u03b11D Adrenoceptor Antagonist with Antiurinary Frequency Effects: Reducing Human Ether-a-go-go-Related Gene (hERG) Liabilities.","doi":"10.1021\/acs.jmedchem.5b01528","doi_url":"https:\/\/doi.org\/10.1021\/acs.jmedchem.5b01528","pmid":"26954848","pmid_url":"https:\/\/pubmed.ncbi.nlm.nih.gov\/26954848\/","year":2016,"journal":"J Med Chem","volume":"59","issue":"7","page":"2989-3002","authors":[{"first_name":"Fujita H","last_name":null,"full_name":null},{"first_name":"Imai S","last_name":null,"full_name":null},{"first_name":"Imai Y","last_name":null,"full_name":null},{"first_name":"Kamo I","last_name":null,"full_name":null},{"first_name":"Kohara Y","last_name":null,"full_name":null},{"first_name":"Kuno H","last_name":null,"full_name":null},{"first_name":"Nagabukuro H","last_name":null,"full_name":null},{"first_name":"Okabe Y","last_name":null,"full_name":null},{"first_name":"Saikawa R","last_name":null,"full_name":null},{"first_name":"Sakauchi N","last_name":null,"full_name":null},{"first_name":"Sato A","last_name":null,"full_name":null},{"first_name":"Suzaki T","last_name":null,"full_name":null},{"first_name":"Yoshida M.","last_name":null,"full_name":null}],"url":"https:\/\/molmedb.upol.cz\/api\/v1\/publications\/2498","landing_page":"https:\/\/molmedb.upol.cz\/publication\/2498","created_at":"2023-06-23T15:08:36.000000Z","updated_at":null}}