{"data":{"id":2487,"citation":"Devasthale P, Wang Y, Wang W, Fevig J, Feng J, Wang A, Harrity T, Egan D, Morgan N, Cap M, Fura A, Klei HE, Kish K, Weigelt C, Sun L, Levesque P, Moulin F, Li YX, Zahler R, Kirby MS, Hamann LG.: Optimization of activity, selectivity, and liability profiles in 5-oxopyrrolopyridine DPP4 inhibitors leading to clinical candidate (Sa)-2-(3-(aminomethyl)-4-(2,4-dichlorophenyl)-2-methyl-5-oxo-5H-pyrrolo[3,4-b]pyridin-6(7H)-yl)-N,N-dimethylacetamide (BMS-767778). J Med Chem, Volume 56 (18), 2013","title":"Optimization of activity, selectivity, and liability profiles in 5-oxopyrrolopyridine DPP4 inhibitors leading to clinical candidate (Sa)-2-(3-(aminomethyl)-4-(2,4-dichlorophenyl)-2-methyl-5-oxo-5H-pyrrolo[3,4-b]pyridin-6(7H)-yl)-N,N-dimethylacetamide (BMS-767778).","doi":"10.1021\/jm4008906","doi_url":"https:\/\/doi.org\/10.1021\/jm4008906","pmid":"23964740","pmid_url":"https:\/\/pubmed.ncbi.nlm.nih.gov\/23964740\/","year":2013,"journal":"J Med Chem","volume":"56","issue":"18","page":"7343-7357","authors":[{"first_name":"Cap M","last_name":null,"full_name":null},{"first_name":"Devasthale P","last_name":null,"full_name":null},{"first_name":"Egan D","last_name":null,"full_name":null},{"first_name":"Feng J","last_name":null,"full_name":null},{"first_name":"Fevig J","last_name":null,"full_name":null},{"first_name":"Fura A","last_name":null,"full_name":null},{"first_name":"Hamann LG.","last_name":null,"full_name":null},{"first_name":"Harrity T","last_name":null,"full_name":null},{"first_name":"Kirby MS","last_name":null,"full_name":null},{"first_name":"Kish K","last_name":null,"full_name":null},{"first_name":"Klei HE","last_name":null,"full_name":null},{"first_name":"Levesque P","last_name":null,"full_name":null},{"first_name":"Li YX","last_name":null,"full_name":null},{"first_name":"Morgan N","last_name":null,"full_name":null},{"first_name":"Moulin F","last_name":null,"full_name":null},{"first_name":"Sun L","last_name":null,"full_name":null},{"first_name":"Wang A","last_name":null,"full_name":null},{"first_name":"Wang W","last_name":null,"full_name":null},{"first_name":"Wang Y","last_name":null,"full_name":null},{"first_name":"Weigelt C","last_name":null,"full_name":null},{"first_name":"Zahler R","last_name":null,"full_name":null}],"url":"https:\/\/molmedb.upol.cz\/api\/v1\/publications\/2487","landing_page":"https:\/\/molmedb.upol.cz\/publication\/2487","created_at":"2023-06-23T15:08:34.000000Z","updated_at":null}}