{"data":{"id":2445,"citation":"Preuss J, Maloney P, Peddibhotla S, Hedrick MP, Hershberger P, Gosalia P, Milewski M, Li YL, Sugarman E, Hood B, Suyama E, Nguyen K, Vasile S, Sergienko E, Mangravita-Novo A, Vicchiarelli M, McAnally D, Smith LH, Roth GP, Diwan J, Chung TD, Jortzik E, Rahlfs S, Becker K, Pinkerton AB, Bode L.: Discovery of a Plasmodium falciparum glucose-6-phosphate dehydrogenase 6-phosphogluconolactonase inhibitor (R,Z)-N-((1-ethylpyrrolidin-2-yl)methyl)-2-(2-fluorobenzylidene)-3-oxo-3,4-dihydro-2H-benzo[b][1,4]thiazine-6-carboxamide (ML276) that reduces parasite growth in vitro. J Med Chem, Volume 55 (16), 2012","title":"Discovery of a Plasmodium falciparum glucose-6-phosphate dehydrogenase 6-phosphogluconolactonase inhibitor (R,Z)-N-((1-ethylpyrrolidin-2-yl)methyl)-2-(2-fluorobenzylidene)-3-oxo-3,4-dihydro-2H-benzo[b][1,4]thiazine-6-carboxamide (ML276) that reduces parasite growth in vitro.","doi":"10.1021\/jm300833h","doi_url":"https:\/\/doi.org\/10.1021\/jm300833h","pmid":"22813531","pmid_url":"https:\/\/pubmed.ncbi.nlm.nih.gov\/22813531\/","year":2012,"journal":"J Med Chem","volume":"55","issue":"16","page":"7262-7272","authors":[{"first_name":"Becker K","last_name":null,"full_name":null},{"first_name":"Bode L.","last_name":null,"full_name":null},{"first_name":"Chung TD","last_name":null,"full_name":null},{"first_name":"Diwan J","last_name":null,"full_name":null},{"first_name":"Gosalia P","last_name":null,"full_name":null},{"first_name":"Hedrick MP","last_name":null,"full_name":null},{"first_name":"Hershberger P","last_name":null,"full_name":null},{"first_name":"Hood B","last_name":null,"full_name":null},{"first_name":"Jortzik E","last_name":null,"full_name":null},{"first_name":"Li YL","last_name":null,"full_name":null},{"first_name":"Maloney P","last_name":null,"full_name":null},{"first_name":"Mangravita-Novo A","last_name":null,"full_name":null},{"first_name":"McAnally D","last_name":null,"full_name":null},{"first_name":"Milewski M","last_name":null,"full_name":null},{"first_name":"Nguyen K","last_name":null,"full_name":null},{"first_name":"Peddibhotla S","last_name":null,"full_name":null},{"first_name":"Pinkerton AB","last_name":null,"full_name":null},{"first_name":"Preuss J","last_name":null,"full_name":null},{"first_name":"Rahlfs S","last_name":null,"full_name":null},{"first_name":"Roth GP","last_name":null,"full_name":null},{"first_name":"Sergienko E","last_name":null,"full_name":null},{"first_name":"Smith LH","last_name":null,"full_name":null},{"first_name":"Sugarman E","last_name":null,"full_name":null},{"first_name":"Suyama E","last_name":null,"full_name":null},{"first_name":"Vasile S","last_name":null,"full_name":null},{"first_name":"Vicchiarelli M","last_name":null,"full_name":null}],"url":"https:\/\/molmedb.upol.cz\/api\/v1\/publications\/2445","landing_page":"https:\/\/molmedb.upol.cz\/publication\/2445","created_at":"2023-06-23T15:08:25.000000Z","updated_at":null}}