{"data":{"id":2226,"citation":"Watterson SH, Xiao Z, Dodd DS, Tortolani DR, Vaccaro W, Potin D, Launay M, Stetsko DK, Skala S, Davis PM, Lee D, Yang X, McIntyre KW, Balimane P, Patel K, Yang Z, Marathe P, Kadiyala P, Tebben AJ, Sheriff S, Chang CY, Ziemba T, Zhang H, Chen BC, DelMonte AJ, Aranibar N, McKinnon M, Barrish JC, Suchard SJ, Murali Dhar TG.: Small molecule antagonist of leukocyte function associated antigen-1 (LFA-1): structure-activity relationships leading to the identification of 6-((5S,9R)-9-(4-cyanophenyl)-3-(3,5-dichlorophenyl)-1-methyl-2,4-dioxo-1,3,7-triazaspiro[4.4]nonan-7-yl)nicotinic acid (BMS-688521). J Med Chem, Volume 53 (9), 2010","title":"Small molecule antagonist of leukocyte function associated antigen-1 (LFA-1): structure-activity relationships leading to the identification of 6-((5S,9R)-9-(4-cyanophenyl)-3-(3,5-dichlorophenyl)-1-methyl-2,4-dioxo-1,3,7-triazaspiro[4.4]nonan-7-yl)nicotinic acid (BMS-688521).","doi":"10.1021\/jm100348u","doi_url":"https:\/\/doi.org\/10.1021\/jm100348u","pmid":"20405922","pmid_url":"https:\/\/pubmed.ncbi.nlm.nih.gov\/20405922\/","year":2010,"journal":"J Med Chem","volume":"53","issue":"9","page":"3814-3830","authors":[{"first_name":"Aranibar N","last_name":null,"full_name":null},{"first_name":"Balimane P","last_name":null,"full_name":null},{"first_name":"Barrish JC","last_name":null,"full_name":null},{"first_name":"Chang CY","last_name":null,"full_name":null},{"first_name":"Chen BC","last_name":null,"full_name":null},{"first_name":"Davis PM","last_name":null,"full_name":null},{"first_name":"DelMonte AJ","last_name":null,"full_name":null},{"first_name":"Dodd DS","last_name":null,"full_name":null},{"first_name":"Kadiyala P","last_name":null,"full_name":null},{"first_name":"Launay M","last_name":null,"full_name":null},{"first_name":"Lee D","last_name":null,"full_name":null},{"first_name":"Marathe P","last_name":null,"full_name":null},{"first_name":"McIntyre KW","last_name":null,"full_name":null},{"first_name":"McKinnon M","last_name":null,"full_name":null},{"first_name":"Murali Dhar TG.","last_name":null,"full_name":null},{"first_name":"Patel K","last_name":null,"full_name":null},{"first_name":"Potin D","last_name":null,"full_name":null},{"first_name":"Sheriff S","last_name":null,"full_name":null},{"first_name":"Skala S","last_name":null,"full_name":null},{"first_name":"Stetsko DK","last_name":null,"full_name":null},{"first_name":"Suchard SJ","last_name":null,"full_name":null},{"first_name":"Tebben AJ","last_name":null,"full_name":null},{"first_name":"Tortolani DR","last_name":null,"full_name":null},{"first_name":"Vaccaro W","last_name":null,"full_name":null},{"first_name":"Watterson SH","last_name":null,"full_name":null},{"first_name":"Xiao Z","last_name":null,"full_name":null},{"first_name":"Yang X","last_name":null,"full_name":null},{"first_name":"Yang Z","last_name":null,"full_name":null},{"first_name":"Zhang H","last_name":null,"full_name":null},{"first_name":"Ziemba T","last_name":null,"full_name":null}],"url":"https:\/\/molmedb.upol.cz\/api\/v1\/publications\/2226","landing_page":"https:\/\/molmedb.upol.cz\/publication\/2226","created_at":"2023-06-23T10:10:36.000000Z","updated_at":null}}