{"data":{"id":2212,"citation":"Ahmad S, Madsen CS, Stein PD, Janovitz E, Huang C, Ngu K, Bisaha S, Kennedy LJ, Chen BC, Zhao R, Sitkoff D, Monshizadegan H, Yin X, Ryan CS, Zhang R, Giancarli M, Bird E, Chang M, Chen X, Setters R, Search D, Zhuang S, Nguyen-Tran V, Cuff CA, Harrity T, Darienzo CJ, Li T, Reeves RA, Blanar MA, Barrish JC, Zahler R, Robl JA.: (3R,5S,E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(methyl(1-methyl-1h-1,2,4-triazol-5-yl)amino)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoic acid (BMS-644950): a rationally designed orally efficacious 3-hydroxy-3-methylglutaryl coenzyme-a reductase inhibitor with reduced myotoxicity potential. J Med Chem, Volume 51 (9), 2008","title":"(3R,5S,E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(methyl(1-methyl-1h-1,2,4-triazol-5-yl)amino)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoic acid (BMS-644950): a rationally designed orally efficacious 3-hydroxy-3-methylglutaryl coenzyme-a reductase inhibitor with reduced myotoxicity potential.","doi":"10.1021\/jm800001n","doi_url":"https:\/\/doi.org\/10.1021\/jm800001n","pmid":"18412317","pmid_url":"https:\/\/pubmed.ncbi.nlm.nih.gov\/18412317\/","year":2008,"journal":"J Med Chem","volume":"51","issue":"9","page":"2722-2733","authors":[{"first_name":"Ahmad S","last_name":null,"full_name":null},{"first_name":"Bird E","last_name":null,"full_name":null},{"first_name":"Bisaha S","last_name":null,"full_name":null},{"first_name":"Chang M","last_name":null,"full_name":null},{"first_name":"Chen BC","last_name":null,"full_name":null},{"first_name":"Chen X","last_name":null,"full_name":null},{"first_name":"Cuff CA","last_name":null,"full_name":null},{"first_name":"Giancarli M","last_name":null,"full_name":null},{"first_name":"Huang C","last_name":null,"full_name":null},{"first_name":"Janovitz E","last_name":null,"full_name":null},{"first_name":"Kennedy LJ","last_name":null,"full_name":null},{"first_name":"Madsen CS","last_name":null,"full_name":null},{"first_name":"Monshizadegan H","last_name":null,"full_name":null},{"first_name":"Ngu K","last_name":null,"full_name":null},{"first_name":"Nguyen-Tran V","last_name":null,"full_name":null},{"first_name":"Ryan CS","last_name":null,"full_name":null},{"first_name":"Search D","last_name":null,"full_name":null},{"first_name":"Setters R","last_name":null,"full_name":null},{"first_name":"Sitkoff D","last_name":null,"full_name":null},{"first_name":"Stein PD","last_name":null,"full_name":null},{"first_name":"Yin X","last_name":null,"full_name":null},{"first_name":"Zhang R","last_name":null,"full_name":null},{"first_name":"Zhao R","last_name":null,"full_name":null},{"first_name":"Zhuang S","last_name":null,"full_name":null},{"first_name":"Barrish JC","last_name":null,"full_name":null},{"first_name":"Blanar MA","last_name":null,"full_name":null},{"first_name":"Darienzo CJ","last_name":null,"full_name":null},{"first_name":"Harrity T","last_name":null,"full_name":null},{"first_name":"Li T","last_name":null,"full_name":null},{"first_name":"Reeves RA","last_name":null,"full_name":null},{"first_name":"Robl JA.","last_name":null,"full_name":null},{"first_name":"Zahler R","last_name":null,"full_name":null}],"url":"https:\/\/molmedb.upol.cz\/api\/v1\/publications\/2212","landing_page":"https:\/\/molmedb.upol.cz\/publication\/2212","created_at":"2023-06-23T10:10:33.000000Z","updated_at":null}}