{"data":{"id":2207,"citation":"Zhang X, Tellew JE, Luo Z, Moorjani M, Lin E, Lanier MC, Chen Y, Williams JP, Saunders J, Lechner SM, Markison S, Joswig T, Petroski R, Piercey J, Kargo W, Malany S, Santos M, Gross RS, Wen J, Jalali K, O'Brien Z, Stotz CE, Crespo MI, D\u00edaz JL, Slee DH.: Lead optimization of 4-acetylamino-2-(3,5-dimethylpyrazol-1-yl)-6-pyridylpyrimidines as A2A adenosine receptor antagonists for the treatment of Parkinson's disease. J Med Chem, Volume 51 (22), 2008","title":"Lead optimization of 4-acetylamino-2-(3,5-dimethylpyrazol-1-yl)-6-pyridylpyrimidines as A2A adenosine receptor antagonists for the treatment of Parkinson's disease.","doi":"10.1021\/jm800851u","doi_url":"https:\/\/doi.org\/10.1021\/jm800851u","pmid":"18947224","pmid_url":"https:\/\/pubmed.ncbi.nlm.nih.gov\/18947224\/","year":2008,"journal":"J Med Chem","volume":"51","issue":"22","page":"7099-7110","authors":[{"first_name":"Chen Y","last_name":null,"full_name":null},{"first_name":"Crespo MI","last_name":null,"full_name":null},{"first_name":"D\u00edaz JL","last_name":null,"full_name":null},{"first_name":"Gross RS","last_name":null,"full_name":null},{"first_name":"Jalali K","last_name":null,"full_name":null},{"first_name":"Joswig T","last_name":null,"full_name":null},{"first_name":"Kargo W","last_name":null,"full_name":null},{"first_name":"Lanier MC","last_name":null,"full_name":null},{"first_name":"Lechner SM","last_name":null,"full_name":null},{"first_name":"Lin E","last_name":null,"full_name":null},{"first_name":"Luo Z","last_name":null,"full_name":null},{"first_name":"Malany S","last_name":null,"full_name":null},{"first_name":"Markison S","last_name":null,"full_name":null},{"first_name":"Moorjani M","last_name":null,"full_name":null},{"first_name":"O'Brien Z","last_name":null,"full_name":null},{"first_name":"Petroski R","last_name":null,"full_name":null},{"first_name":"Piercey J","last_name":null,"full_name":null},{"first_name":"Santos M","last_name":null,"full_name":null},{"first_name":"Saunders J","last_name":null,"full_name":null},{"first_name":"Slee DH.","last_name":null,"full_name":null},{"first_name":"Stotz CE","last_name":null,"full_name":null},{"first_name":"Tellew JE","last_name":null,"full_name":null},{"first_name":"Wen J","last_name":null,"full_name":null},{"first_name":"Williams JP","last_name":null,"full_name":null},{"first_name":"Zhang X","last_name":null,"full_name":null}],"url":"https:\/\/molmedb.upol.cz\/api\/v1\/publications\/2207","landing_page":"https:\/\/molmedb.upol.cz\/publication\/2207","created_at":"2023-06-23T10:10:31.000000Z","updated_at":null}}