{"data":{"id":2185,"citation":"Murugesan N, Gu Z, Spergel S, Young M, Chen P, Mathur A, Leith L, Hermsmeier M, Liu EC, Zhang R, Bird E, Waldron T, Marino A, Koplowitz B, Humphreys WG, Chong S, Morrison RA, Webb ML, Moreland S, Trippodo N, Barrish JC.: Biphenylsulfonamide endothelin receptor antagonists. 4. Discovery of N-[[2'-[[(4,5-dimethyl-3-isoxazolyl)amino]sulfonyl]-4-(2-oxazolyl)[1,1'-biphenyl]- 2-yl]methyl]-N,3,3-trimethylbutanamide (BMS-207940), a highly potent and orally active ET(A) selective antagonist. J Med Chem, Volume 46 (1), 2003","title":"Biphenylsulfonamide endothelin receptor antagonists. 4. Discovery of N-[[2'-[[(4,5-dimethyl-3-isoxazolyl)amino]sulfonyl]-4-(2-oxazolyl)[1,1'-biphenyl]- 2-yl]methyl]-N,3,3-trimethylbutanamide (BMS-207940), a highly potent and orally active ET(A) selective antagonist.","doi":"10.1021\/jm020289q","doi_url":"https:\/\/doi.org\/10.1021\/jm020289q","pmid":"12502366","pmid_url":"https:\/\/pubmed.ncbi.nlm.nih.gov\/12502366\/","year":2003,"journal":"J Med Chem","volume":"46","issue":"1","page":"125-137","authors":[{"first_name":"Barrish JC.","last_name":null,"full_name":null},{"first_name":"Bird E","last_name":null,"full_name":null},{"first_name":"Chen P","last_name":null,"full_name":null},{"first_name":"Chong S","last_name":null,"full_name":null},{"first_name":"Gu Z","last_name":null,"full_name":null},{"first_name":"Hermsmeier M","last_name":null,"full_name":null},{"first_name":"Humphreys WG","last_name":null,"full_name":null},{"first_name":"Koplowitz B","last_name":null,"full_name":null},{"first_name":"Leith L","last_name":null,"full_name":null},{"first_name":"Liu EC","last_name":null,"full_name":null},{"first_name":"Marino A","last_name":null,"full_name":null},{"first_name":"Mathur A","last_name":null,"full_name":null},{"first_name":"Moreland S","last_name":null,"full_name":null},{"first_name":"Morrison RA","last_name":null,"full_name":null},{"first_name":"Murugesan N","last_name":null,"full_name":null},{"first_name":"Spergel S","last_name":null,"full_name":null},{"first_name":"Trippodo N","last_name":null,"full_name":null},{"first_name":"Waldron T","last_name":null,"full_name":null},{"first_name":"Webb ML","last_name":null,"full_name":null},{"first_name":"Young M","last_name":null,"full_name":null},{"first_name":"Zhang R","last_name":null,"full_name":null}],"url":"https:\/\/molmedb.upol.cz\/api\/v1\/publications\/2185","landing_page":"https:\/\/molmedb.upol.cz\/publication\/2185","created_at":"2023-06-23T10:10:26.000000Z","updated_at":null}}