{"data":{"id":2145,"citation":"Raboisson P, de Kock H, Rosenquist A, Nilsson M, Salvador-Oden L, Lin TI, Roue N, Ivanov V, W\u00e4hling H, Wickstr\u00f6m K, Hamelink E, Edlund M, Vrang L, Vendeville S, Van de Vreken W, McGowan D, Tahri A, Hu L, Boutton C, Lenz O, Delouvroy F, Pille G, Surleraux D, Wigerinck P, Samuelsson B, Simmen K.: Structure-activity relationship study on a novel series of cyclopentane-containing macrocyclic inhibitors of the hepatitis C virus NS3\/4A protease leading to the discovery of TMC435350. Bioorg Med Chem Lett, Volume 18 (17), 2008","title":"Structure-activity relationship study on a novel series of cyclopentane-containing macrocyclic inhibitors of the hepatitis C virus NS3\/4A protease leading to the discovery of TMC435350.","doi":"10.1016\/j.bmcl.2008.07.088","doi_url":"https:\/\/doi.org\/10.1016\/j.bmcl.2008.07.088","pmid":"18678486","pmid_url":"https:\/\/pubmed.ncbi.nlm.nih.gov\/18678486\/","year":2008,"journal":"Bioorg Med Chem Lett","volume":"18","issue":"17","page":"4853-4858","authors":[{"first_name":"Boutton C","last_name":null,"full_name":null},{"first_name":"de Kock H","last_name":null,"full_name":null},{"first_name":"Delouvroy F","last_name":null,"full_name":null},{"first_name":"Edlund M","last_name":null,"full_name":null},{"first_name":"Hamelink E","last_name":null,"full_name":null},{"first_name":"Hu L","last_name":null,"full_name":null},{"first_name":"Ivanov V","last_name":null,"full_name":null},{"first_name":"Lenz O","last_name":null,"full_name":null},{"first_name":"Lin TI","last_name":null,"full_name":null},{"first_name":"McGowan D","last_name":null,"full_name":null},{"first_name":"Nilsson M","last_name":null,"full_name":null},{"first_name":"Pille G","last_name":null,"full_name":null},{"first_name":"Raboisson P","last_name":null,"full_name":null},{"first_name":"Rosenquist A","last_name":null,"full_name":null},{"first_name":"Roue N","last_name":null,"full_name":null},{"first_name":"Salvador-Oden L","last_name":null,"full_name":null},{"first_name":"Samuelsson B","last_name":null,"full_name":null},{"first_name":"Simmen K.","last_name":null,"full_name":null},{"first_name":"Surleraux D","last_name":null,"full_name":null},{"first_name":"Tahri A","last_name":null,"full_name":null},{"first_name":"Van de Vreken W","last_name":null,"full_name":null},{"first_name":"Vendeville S","last_name":null,"full_name":null},{"first_name":"Vrang L","last_name":null,"full_name":null},{"first_name":"W\u00e4hling H","last_name":null,"full_name":null},{"first_name":"Wickstr\u00f6m K","last_name":null,"full_name":null},{"first_name":"Wigerinck P","last_name":null,"full_name":null}],"url":"https:\/\/molmedb.upol.cz\/api\/v1\/publications\/2145","landing_page":"https:\/\/molmedb.upol.cz\/publication\/2145","created_at":"2023-06-23T10:10:18.000000Z","updated_at":null}}