{"data":{"id":2047,"citation":"Singh J, Zeller W, Zhou N, Hategan G, Mishra RK, Polozov A, Yu P, Onua E, Zhang J, Ram\u00edrez JL, Sigthorsson G, Thorsteinnsdottir M, Kiselyov AS, Zembower DE, Andr\u00e9sson T, Gurney ME.: Structure-activity relationship studies leading to the identification of (2E)-3-[l-[(2,4-dichlorophenyl)methyl]-5-fluoro-3-methyl-lH-indol-7-yl]-N-[(4,5-dichloro-2-thienyl)sulfonyl]-2-propenamide (DG-041), a potent and selective prostanoid EP3 receptor antagonist, as a novel antiplatelet agent that does not prolong bleeding. J Med Chem, Volume 53 (1), 2010","title":"Structure-activity relationship studies leading to the identification of (2E)-3-[l-[(2,4-dichlorophenyl)methyl]-5-fluoro-3-methyl-lH-indol-7-yl]-N-[(4,5-dichloro-2-thienyl)sulfonyl]-2-propenamide (DG-041), a potent and selective prostanoid EP3 receptor antagonist, as a novel antiplatelet agent that does not prolong bleeding.","doi":"10.1021\/jm9005912","doi_url":"https:\/\/doi.org\/10.1021\/jm9005912","pmid":"19957930","pmid_url":"https:\/\/pubmed.ncbi.nlm.nih.gov\/19957930\/","year":2010,"journal":"J Med Chem","volume":"53","issue":"1","page":"18-36","authors":[{"first_name":"Andr\u00e9sson T","last_name":null,"full_name":null},{"first_name":"Gurney ME.","last_name":null,"full_name":null},{"first_name":"Hategan G","last_name":null,"full_name":null},{"first_name":"Kiselyov AS","last_name":null,"full_name":null},{"first_name":"Mishra RK","last_name":null,"full_name":null},{"first_name":"Onua E","last_name":null,"full_name":null},{"first_name":"Polozov A","last_name":null,"full_name":null},{"first_name":"Ram\u00edrez JL","last_name":null,"full_name":null},{"first_name":"Sigthorsson G","last_name":null,"full_name":null},{"first_name":"Singh J","last_name":null,"full_name":null},{"first_name":"Thorsteinnsdottir M","last_name":null,"full_name":null},{"first_name":"Yu P","last_name":null,"full_name":null},{"first_name":"Zeller W","last_name":null,"full_name":null},{"first_name":"Zembower DE","last_name":null,"full_name":null},{"first_name":"Zhang J","last_name":null,"full_name":null},{"first_name":"Zhou N","last_name":null,"full_name":null}],"url":"https:\/\/molmedb.upol.cz\/api\/v1\/publications\/2047","landing_page":"https:\/\/molmedb.upol.cz\/publication\/2047","created_at":"2023-06-23T10:09:57.000000Z","updated_at":null}}