{"data":{"id":1423,"citation":"Ehara T, Irie O, Kosaka T, Kanazawa T, Breitenstein W, Grosche P, Ostermann N, Suzuki M, Kawakami S, Konishi K, Hitomi Y, Toyao A, Gunji H, Cumin F, Schiering N, Wagner T, Rigel DF, Webb RL, Maibaum J, Yokokawa F.: Structure-based design of substituted piperidines as a new class of highly efficacious oral direct Renin inhibitors. ACS Med Chem Lett, Volume 5 (7), 2014","title":"Structure-based design of substituted piperidines as a new class of highly efficacious oral direct Renin inhibitors.","doi":"10.1021\/ml500137b","doi_url":"https:\/\/doi.org\/10.1021\/ml500137b","pmid":"25050166","pmid_url":"https:\/\/pubmed.ncbi.nlm.nih.gov\/25050166\/","year":2014,"journal":"ACS Med Chem Lett","volume":"5","issue":"7","page":"787-792","authors":[{"first_name":"Breitenstein W","last_name":null,"full_name":null},{"first_name":"Cumin F","last_name":null,"full_name":null},{"first_name":"Ehara T","last_name":null,"full_name":null},{"first_name":"Grosche P","last_name":null,"full_name":null},{"first_name":"Gunji H","last_name":null,"full_name":null},{"first_name":"Hitomi Y","last_name":null,"full_name":null},{"first_name":"Irie O","last_name":null,"full_name":null},{"first_name":"Kanazawa T","last_name":null,"full_name":null},{"first_name":"Kawakami S","last_name":null,"full_name":null},{"first_name":"Konishi K","last_name":null,"full_name":null},{"first_name":"Kosaka T","last_name":null,"full_name":null},{"first_name":"Maibaum J","last_name":null,"full_name":null},{"first_name":"Ostermann N","last_name":null,"full_name":null},{"first_name":"Rigel DF","last_name":null,"full_name":null},{"first_name":"Schiering N","last_name":null,"full_name":null},{"first_name":"Suzuki M","last_name":null,"full_name":null},{"first_name":"Toyao A","last_name":null,"full_name":null},{"first_name":"Wagner T","last_name":null,"full_name":null},{"first_name":"Webb RL","last_name":null,"full_name":null},{"first_name":"Yokokawa F.","last_name":null,"full_name":null}],"url":"https:\/\/molmedb.upol.cz\/api\/v1\/publications\/1423","landing_page":"https:\/\/molmedb.upol.cz\/publication\/1423","created_at":"2021-01-20T12:16:37.000000Z","updated_at":null}}