{"data":{"id":1212,"citation":"Hirsh AJ, Molino BF, Zhang J, Astakhova N, Geiss WB, Sargent BJ, Swenson BD, Usyatinsky A, Wyle MJ, Boucher RC, Smith RT, Zamurs A, Johnson MR.: Design, synthesis, and structure-activity relationships of novel 2-substituted pyrazinoylguanidine epithelial sodium channel blockers: drugs for cystic fibrosis and chronic bronchitis. J Med Chem, Volume 49 (14), 2006","title":"Design, synthesis, and structure-activity relationships of novel 2-substituted pyrazinoylguanidine epithelial sodium channel blockers: drugs for cystic fibrosis and chronic bronchitis.","doi":"10.1021\/jm051134w","doi_url":"https:\/\/doi.org\/10.1021\/jm051134w","pmid":"16821771","pmid_url":"https:\/\/pubmed.ncbi.nlm.nih.gov\/16821771\/","year":2006,"journal":"J Med Chem","volume":"49","issue":"14","page":"4098-4115","authors":[{"first_name":"Astakhova N","last_name":null,"full_name":null},{"first_name":"Boucher RC","last_name":null,"full_name":null},{"first_name":"Geiss WB","last_name":null,"full_name":null},{"first_name":"Hirsh AJ","last_name":null,"full_name":null},{"first_name":"Johnson MR.","last_name":null,"full_name":null},{"first_name":"Molino BF","last_name":null,"full_name":null},{"first_name":"Sargent BJ","last_name":null,"full_name":null},{"first_name":"Smith RT","last_name":null,"full_name":null},{"first_name":"Swenson BD","last_name":null,"full_name":null},{"first_name":"Usyatinsky A","last_name":null,"full_name":null},{"first_name":"Wyle MJ","last_name":null,"full_name":null},{"first_name":"Zamurs A","last_name":null,"full_name":null},{"first_name":"Zhang J","last_name":null,"full_name":null}],"url":"https:\/\/molmedb.upol.cz\/api\/v1\/publications\/1212","landing_page":"https:\/\/molmedb.upol.cz\/publication\/1212","created_at":"2021-01-20T08:40:53.000000Z","updated_at":null}}