{"data":{"id":34,"name":"Solid-Phase Microextraction","abbreviation":"Microextraction","description":"<p style=\"text-align: justify;\">Solid-phase microextraction (SPME) is a solvent-free sample preparation technique used to extract and preconcentrate analytes from liquid or gaseous samples before instrumental analysis. The method employs a thin fiber coated with a polymer or solid sorbent, which selectively adsorbs or absorbs target compounds. During extraction, analytes partition between the sample and the coating until equilibrium, or a defined pre-equilibrium state, is reached. The amount extracted is proportional to the analyte concentration in the sample. After extraction, the fiber is transferred directly into the injection port of an analytical instrument, typically gas chromatography (GC) or gas chromatography\u2013mass spectrometry (GC\u2013MS), where the analytes are thermally desorbed and analyzed. SPME is fast, simple, highly sensitive, requires no organic solvents, and combines sampling, extraction, and preconcentration into a single step.<\/p>","categories":[{"id":7,"title":"Partitioning","breadcrumb":[{"id":4,"title":"Experimental"},{"id":7,"title":"Partitioning"}]}],"url":"https:\/\/molmedb.upol.cz\/api\/v1\/methods\/34","landing_page":"https:\/\/molmedb.upol.cz\/method\/34","created_at":"2018-11-06T13:49:05.000000Z","updated_at":"2026-07-02T10:04:10.000000Z"}}