{"data":{"id":55,"name":"dipalmitoylphosphatidylcholine : dipalmitoylphosphatidylglycerol : cholesterol membrane","abbreviation":"DPPC_DPPG_CHOL","description":"<p>Ternary bilayers combining dipalmitoylphosphatidylcholine (DPPC), dipalmitoylphosphatidylglycerol (DPPG), and cholesterol (CHOL) merge saturated neutral lipid structure, negative charge, and sterol ordering. DPPC provides a tightly packed matrix, while DPPG introduces anionic headgroups that influence electrostatics and promote lateral heterogeneity. CHOL condenses packing, increases membrane order, and reduces permeability by filling void spaces between lipid acyl chains. The negative charge from DPPG can cause phase separation or domain formation, especially in presence of CHOL, which may segregate into neutral or less charged regions. Such mixtures serve as biophysically relevant models of charged plasma membranes and allow exploration of how charge, order, and sterol content jointly modulate permeability and solute partitioning.<\/p>","categories":[{"id":153,"title":"Model","breadcrumb":[{"id":152,"title":"Cell"},{"id":153,"title":"Model"}]}],"url":"https:\/\/molmedb.upol.cz\/api\/v1\/membranes\/55","landing_page":"https:\/\/molmedb.upol.cz\/membrane\/55","created_at":"2023-04-28T04:25:13.000000Z","updated_at":"2026-06-29T12:31:43.000000Z"}}